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Growth Hormone-Releasing Peptides and Their Analogs

MS Akman et al. Mechanisms of action of a second generation growth hormone-releasing peptide (Ala-His-dd Endocrinology (1993) JA Aloi et al. Neuroendocrine responses to a novel growth hormone secretagogue, L-692,429, in healthy older subjects J Clin Endocrinol Metab (1994) DK Alster et al. The growth hormone (GH) response to GH-releasing peptide (His-dd J Clin Endocrinol Metab (1993) M Arosio et al. Effects of Hexarelin (EP23905-MF6003) on circulating GH levels in acromegalic patients. (Highlights inMol Clin Endocrinol Front Endocrinol (1994) E Arvat et al. Arginine and growth hormone-releasing hormone restore the blunted growth hormone-releasing activity of hexarelin in elderly subjects J Clin Endocrinol Metab (1994) E Arvat et al. Modulation of growth hormone-releasing activity of hexarelin in man Neuroendocrinology (1995) E Arvat et al. Supramaximal doses of GHRH or Hexarelin, a synthetic hexapeptide, enhance the low somatotrope responsiveness in aging J Endocrinol Invest (1996) E A

Context first

Study findings do not automatically establish clinical benefit, safety, dosing, or suitability for an individual.

MS Akman et al.

Mechanisms of action of a second generation growth hormone-releasing peptide (Ala-His-dd

Endocrinology

(1993) JA Aloi et al.

Neuroendocrine responses to a novel growth hormone secretagogue, L-692,429, in healthy older subjects

J Clin Endocrinol Metab

(1994) DK Alster et al.

The growth hormone (GH) response to GH-releasing peptide (His-dd

J Clin Endocrinol Metab

(1993) M Arosio et al.

Effects of Hexarelin (EP23905-MF6003) on circulating GH levels in acromegalic patients. (Highlights inMol Clin Endocrinol

Front Endocrinol

(1994) E Arvat et al.

Arginine and growth hormone-releasing hormone restore the blunted growth hormone-releasing activity of hexarelin in elderly subjects

J Clin Endocrinol Metab

(1994) E Arvat et al.

Modulation of growth hormone-releasing activity of hexarelin in man

Neuroendocrinology

(1995) E Arvat et al.

Supramaximal doses of GHRH or Hexarelin, a synthetic hexapeptide, enhance the low somatotrope responsiveness in aging

J Endocrinol Invest

(1996) E Arvat et al.

Influence of beta-adrenergic agonists and antagonists on the GH-releasing effect of Hexarelin in man

J Endocrinol Invest

(1996) E Arvat et al.

Oestrogen replacement does not restore the reduced GH-releasing activity of hexarelin, a synthetic hexapeptide, in postmenopausal women

Eur J Endocrinol

(1997) E Arvat et al.

Effects of histaminergic antagonists on the GH-releasing activity of GHRH or hexarelin, a synthetic hexapeptide, in man

J Endocrinol Invest

(1997) TM Badger et al.

The effects of growth hormone (GH)-releasing peptides on GH secretion in perifused pituitary cells of adult male rats

Endocrinology

(1984) AD Blake et al.

Desensitization studies using perifused rat pituitary cells show that growth hormone-releasing hormone and His-dd

J Endocrinol

(1991) J Bellone et al.

Growth hormone-releasing activity of Hexarelin, a new synthetic hexapeptide, before and during puberty

J Clin Endocrinol Metab

(1995) J Bellone et al.

Growth hormone-releasing effect of oral growth hormone-releasing peptide 6 (GHRP-6) administration in children with short stature

Eur J Endocrinol

(1995) BB Bercu et al.

Sex differences in growth hormone (GH) secretion by rats administered GH-releasing hexapeptide

Endocrinology

(1991) BB Bercu et al.

Role of selected endogenous peptides in growth hormone-releasing hexapeptide activity: Analysis of growth hormone-releasing hormone, thyroid hormone-releasing hormone, and gonadotropin-releasing hormone

Endocrinology

(1992) CY Bowers et al.

On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone

Endocrinology

(1984) CY Bowers et al.

Growth hormone (GH)-releasing peptide stimulates GH release in normal men and acts synergistically with GH-releasing hormone

J Clin Endocrinol Metab

(1990) CY Bowers et al.

On the action of the growth hormone-releasing hexapeptide, GHRP

Endocrinology

(1991) CY Bowers et al.

The growth hormone-releasing activity of a synthetic hexapeptide in normal men and short statured children after oral administration

J Clin Endocrinol Metab

(1992) CY Bowers et al.

Atypical growth hormone releasing peptides

Growth Hormone II, Basic and Clinical Aspects

(1993) CY Bowers

GH releasing peptides: Structure and kinetics

J Pediatr Endocrinol

(1993) CY Bowers

Novel GH-releasing peptides M Cappa et al.

Exogenous growth hormone administration does not inhibit the growth hormone response to Hexarelin in normal men

J Endocrinol Invest

(1995) CH Chang et al.

Activity of a novel non peptidyl GH secretagogue, L-700,653, in swine

Endocrinology

(1995) Chang, C, H, Faidley, T, Rickes, L, McGuire, L, A, Nicolich, S, Murphy, T, Frazier, E, Chen, H, Smith, R, G, Hickey, J,... IM Chapman et al.

Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretagogue (MK-677) in healthy elderly subjects

J Clin Endocrinol Metab

(1996) IM Chapman et al.

Enhancement of pulsatile growth hormone secretory by continous infusion of a growth hormone-releasing peptide mimetic, L-692,429, in older adults—A clinical research center study

J Clin Endocrinol Metab

(1996) Chapman, I, M, Pescovitz, O, H, Treep, T, Murphy, G, Cerchio, K, Krupa, D, Gertz, B, Polvino, W, Skiles, E, H, Pezzoli,... P Chatelain et al.

Fetal and neonatal somatotroph function

Front Paediatr Neuroendocrinol

(1994) K Cheng et al.

The synergistic effects of His-dd

Endocrinology

(1989) K Cheng et al.

A novel non-peptidyl growth hormone secretagogue

Horm Res

(1993) K Cheng et al.

Stimulation of growth hormone release from rat primary pituitary cells by L-692,429, a novel non-peptidyl GH secretagogue

Endocrinology

(1993) K Chihara et al.

Growth hormone releasing hexapeptide: Basic research and clinical application E Ciccarelli et al.

Hexarelin, a synthetic growth hormone releasing peptide, stimulates prolactin secretion in acromegalic but not in hyperprolactinemia patients

Clin Endocrinol

(1996) RG Clark et al.

The effects of a growth hormone-releasing peptide and growth hormone-releasing factor in conscious and anaesthetized rats

J Neuroendocrinol

(1989) Clark, R, G, Mortenesen, D, L, Won, W, B, Ma, Y, H, Stanley, M, S, Somers, T, C, Fairhall, K, M, Thoams, G, B,... LK Conley et al.

Mechanism of action of Hexarelin and GHRP-6: Analysis of the involvement of GHRH and somatostatin in the rat

Neuroendocrinology

(1995) G Copinschi et al.

Effects of 7-day treatment with a novel, orally active, growth hormone (GH) secretagogue, MK-677, on 24-hour GH profiles, insulin-like growth factor I, and adrenocortical function in normal young men

J Clin Endocrinol Metab

(1996) F Cordido et al.

Massive growth hormone (GH) discharge in obese subjects after the combined administration of GH-releasing hormone and GHRP-6: Evidence for a marked somatotroph secretory capability in obesity

J Clin Endocrinol Metab

(1993)

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