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KEGG DRUG: Tesamorelin

Entry D06655 Drug Name Tesamorelin (USAN) Formula C221H366N72O67S Exact mass 5132.7166 Mol weight 5135.78 Sequence C6H9O-Tyr Ala Asp Ala Ile Phe Thr Asn Ser Tyr Arg Lys Leu Gly Gln Leu Ser Ala Arg Lys Leu Leu Gln Asp Ile Met Ser Arg Gln Gln Gly Glu Ser Asn Gln Glu Arg Gly Ala Arg Ala Arg Leu-NH2 Type Peptide Remark ATC code: H01AC06 Chemical structure group: DG00495 Product (DG00495): D09015 Efficacy Growth hormone releasing hormone receptor agonist Comment growth hormone-releasing hormone (GH-RH) [HSA:2691] [KO:K05260] analog For reduction of visceral adipose tissue in patients receiving antiretroviral therapy Target GHRHR [HSA:2692] [KO:K04584] Pathway hsa04080 Neuroactive ligand-receptor interaction Brite Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS H01 PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES H01A ANTERIOR PITUITARY LOBE HORMONES AND ANALOGUES H01AC Somatropin and somatropin agonists H01

Context first

Study findings do not automatically establish clinical benefit, safety, dosing, or suitability for an individual.

Entry

D06655 Drug Name

Tesamorelin (USAN) Formula

C221H366N72O67S Exact mass

5132.7166 Mol weight

5135.78 Sequence

C6H9O-Tyr Ala Asp Ala Ile Phe Thr Asn Ser Tyr Arg Lys Leu Gly Gln Leu Ser Ala Arg Lys Leu Leu Gln Asp Ile Met Ser Arg Gln Gln Gly Glu Ser Asn Gln Glu Arg Gly Ala Arg Ala Arg Leu-NH2 Type

Peptide Remark

ATC code: H01AC06

Chemical structure group: DG00495

Product (DG00495): D09015<US> Efficacy

Growth hormone releasing hormone receptor agonist Comment

growth hormone-releasing hormone (GH-RH) [HSA:2691] [KO:K05260] analog For reduction of visceral adipose tissue in patients receiving antiretroviral therapy Target

GHRHR [HSA:2692] [KO:K04584] Pathway

hsa04080 Neuroactive ligand-receptor interaction Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS H01 PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES H01A ANTERIOR PITUITARY LOBE HORMONES AND ANALOGUES H01AC Somatropin and somatropin agonists H01AC06 Tesamorelin D06655 Tesamorelin (USAN) Target-based classification of drugs [BR:br08310] G Protein-coupled receptors Secretin receptor family Growth hormone-releasing hormone GHRHR D06655 Tesamorelin (USAN) Other DBs

CAS: 218949-48-5

PubChem: 47208306

ChEBI: 63626

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