IGF-1 LR3 Dosing Protocol: 1 mg Vial — Daily Dosing Schedule & Supplies
Complete IGF-1 LR3 dosing guide for the 1 mg vial, including acetic acid reconstitution technique, dosing table, and cycle protocol.
Quickstart highlights
IGF-1 LR3 is a 83-amino acid analogue of IGF-1 with an N-terminal Arg extension and Glu3→Arg3 substitution.
Concentration: 1 mg/mL (1 mg vial dissolved in acetic acid then diluted with bacteriostatic water).
At 1 mg/mL: 50 μg = 5 units, 100 μg = 10 units on U-100 syringe.
Requires dilute acetic acid (0.1M) as primary solvent — NOT bacteriostatic water alone.
Maximum cycle: 4 weeks; longer cycles risk receptor desensitization.
ALWAYS have fast-acting carbohydrates available post-injection — hypoglycemia risk.
Dosing table
For educational reference only. Your prescribing provider may adjust doses based on your clinical profile and response.
1-2
20
2
Once daily post-workout
20 μg — 2 units; conservative start to assess hypoglycemia sensitivity; have food ready
3-4
50
5
50 μg — 5 units; standard starting dose; inject within 30 minutes of training
5-8
100
10
100 μg — 10 units; maximum recommended dose; monitor for hypoglycemia
Your free IGF-1 LR3 tracker
Dose reminders
Injection logging
Cycle progress
Reconstitution steps
IGF-1 LR3 requires dilute acetic acid (0.1M, ~0.6% solution) as the initial solvent — NOT bacteriostatic water. Dissolve with 100 μL (0.1 mL) acetic acid first.
Once fully dissolved in acetic acid, dilute to final volume with bacteriostatic water to reach 1 mg/mL (add 0.9 mL bac water for a total of 1 mL).
Final concentration: 1 mg/mL = 1,000 μg/mL. At 1 mg/mL: 50 μg = 5 units, 100 μg = 10 units on a U-100 syringe.
Label with date; refrigerate at 2–8 °C. Use within 30 days. Do not freeze.
Supplies needed
4-week plan
1 vial
28 syringes
1 mL bac water
28 alcohol swabs
Protocol overview & cycle notes
Promote satellite cell activation and muscle protein synthesis through short-acting IGF-1 LR3 cycles, using post-workout subcutaneous injection timed to exercise-induced receptor upregulation.
Cycle length: 4 weeks on.
Off-cycle: 4+ weeks off; IGF-1 LR3 cycles should not exceed 4 weeks without a break to prevent receptor desensitization.
Storage & handling
Injection & tracking tips
Inject subcutaneously within 30 minutes post-workout to leverage exercise-enhanced GLUT4 expression and minimize hypoglycemia risk.
ALWAYS have fast-acting carbohydrates available (glucose tablets, juice) immediately after injection — IGF-1 LR3 can cause significant hypoglycemia, especially in fasted state.
Never inject IGF-1 LR3 in a fasted state; a post-workout protein + carbohydrate meal should immediately follow injection.
Tracking
Logging helps you and your provider spot patterns and adjust dose or timing.
Monitor blood glucose 30 and 60 minutes post-injection for the first 2 weeks — hypoglycemia risk is highest in this window.
Track muscle soreness (DOMS) recovery time; IGF-1 LR3 typically accelerates recovery by 20–30% when working.
Measure IGF-1 serum levels before starting and after 2 weeks to confirm systemic exposure.
How this works & references
Sources
Source: Tomas FM et al. — Long R3 IGF-I: potency and half-life in rats. Growth Factors. 1993
Source: Jacobs JW et al. — IGF binding protein-3 interactions with LR3-IGF-1. J Endocrinol. 1997
Frequently asked questions
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This content is for informational purposes only and does not constitute medical advice. Consult a licensed healthcare provider before starting any peptide therapy. Dosing and protocols may vary by formulation and prescriber.
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