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Reviewed on August 20, 2025
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Brand Names
Egrifta, Egrifta SV, Egrifta WR
Generic Name
tesamorelin acetate
Phonetic Name
(TES-a-moe-REL-in)
Clinical Uses
This medication is used to reduce excess fat in the stomach area (abdomen) in people with HIV infection who have changes in the way their body fat is distributed. Some HIV drugs may cause this side effect (increased fat in the upper back and stomach areas, decreased fat in the arms and legs). Tesamorelin works by causing your body to make more growth hormone. This medication should not be used for weight loss.
Form Dose: 0.7 to 1 each
Metric Dose: 1.4 milligram
Form Dose: 0.7 to 1 each
Metric Dose: 1.4 milligram
2 mg
Brand(s): (of Egrifta SV(R) 10 mL
Brand(s): subcutaneous of diluent (sterile water for use injection)), Theratechnologies
Read the Patient Information Leaflet and Instructions for Use if available from your pharmacist before you start this medication and each time you get a refill. Ask your health care professional how to prepare and use this medication. If you have any questions, ask your doctor or pharmacist. Inject this medication under the skin as directed by your doctor, usually once daily. The injection is given in the stomach (abdomen). Before using, check this product for particles or discoloration. If either is present, do not use the liquid. Before injecting each dose, clean the skin you are going to inject into (the injection site) with rubbing alcohol. Change the injection site each time to lessen injury under the skin. Do not inject into skin that is scarred, bruised, red, or irritated. To lessen bruising, do not rub the injection site after a shot. Learn how to store and discard medical supplies safely. There are different brands and strengths of this medication. Do not switch to a different brand without your doctor's approval. Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day.
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.
Do not use this drug if you become pregnant. Breast milk may transmit your infection to your infant. Consult your doctor or pharmacist before breastfeeding. Do not refrigerate. Protect from light
Fda Approved:
Certain:
lipodystrophy associated with human immunodeficiency virus infection
Somewhat Certain:
Uncertain:
Non Fda Approved:
Certain:
Somewhat Certain:
Uncertain:
Clinical Uses:
This medication is used to reduce excess fat in the stomach area (abdomen) in people with HIV infection who have changes in the way their body fat is distributed. Some HIV drugs may cause this side effect (increased fat in the upper back and stomach areas, decreased fat in the arms and legs). Tesamorelin works by causing your body to make more growth hormone. This medication should not be used for weight loss.
hypothalamic-pituitary insufficiency lactation malignancy pituitary insufficiency pregnancy radiation therapy of cranium transsphenoidal hypophysectomy
acute respiratory failure diabetes mellitus edema
Arthralgia Body fluid retention Hyperglycemia Injection site erythema Injection site sequelae Myalgia Peripheral edema
Abdominal pain with cramps Carpal tunnel syndrome Depression Dyspepsia Flushing Hypertension Hypoesthesia Insomnia Musculoskeletal pain Nausea Night sweats Pain Pain in extremities Palpitations Paresthesia Pruritus of skin Skin rash Urticaria Vomiting
"The manufacturer states that there is no information on the use of tesamorelin in patients older than 65 years of age with HIV-associated lipodystrophy. "
Precaution Severity Narrative TESAMORELIN Contraindicated Contraindicated during pregnancy. Insufficient human data available on developmental toxicity risk. Immediately discontinue treatment in pregnant patients. Based on animal data, fetal harm may occur.
Severity Narrative Absolute Contraindication MFG DOES NOT RECOMMEND BREASTFEEDING IN HIV-POSITIVE WOMEN
Severity Narrative Management or Monitoring Precaution No safety and efficacy. Risk of growth acceleration with open epiphyses.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Different brands of this medication have different storage needs. Check the product package for instructions on how to store your brand, or ask your pharmacist. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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Selected from data included with permission and copyrighted by FDB, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution in professional health care settings.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of your healthcare professional. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you. You should consult your healthcare professional before taking any drug, changing your diet or commencing or discontinuing any course of treatment. See our full terms of use.
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking any drug or commencing or discontinuing any course of treatment.