HomeShopGrowth & RepairIGF-1LR3
Growth & Repair
99%+ Purity USA TestedResearch Use Only. Not for Human or Veterinary Use
1mg research peptide
$109.00
1
Size 1mg
99%+ Purity
USA Lab Tested
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Specifications
IGF-1LR3 Technical Profile
OVERVIEW
What Is IGF-1 LR3 Peptide?
IGF-1 LR3 (Insulin-like Growth Factor 1 Long R3) is an 83-amino-acid synthetic variant of human IGF-1, engineered with two key structural modifications: a glutamic acid substitution for arginine at position 3 (R3) and a 13-amino-acid N-terminal extension peptide. These modifications were designed to reduce binding affinity for IGF binding proteins (IGFBPs), which normally sequester circulating IGF-1 and limit its bioavailability. As a result, IGF-1 LR3 exhibits a significantly extended functional half-life compared to native IGF-1 in research systems.
IGF-1 LR3 peptide is one of the most widely used growth factor analogs in cell biology and tissue culture research. Its reduced IGFBP binding means that a greater proportion of the peptide remains free to interact with the IGF-1 receptor (IGF-1R), making it a more potent and predictable tool for in vitro research. Published studies utilizing IGF-1 LR3 span cell proliferation, differentiation, survival signaling, and metabolic research, reflecting the peptide's broad utility in growth factor biology.
RESEARCH
IGF-1 LR3 Mechanism of Action in Research
The IGF-1 LR3 mechanism of action parallels that of native IGF-1 but with enhanced potency due to its reduced IGFBP sequestration. Published research has extensively characterized IGF-1 LR3's interaction with the IGF-1 receptor and its downstream signaling cascades. IGF-1 LR3 research provides valuable data on growth factor signaling in contexts where extended receptor activation is experimentally desirable.
COMPARISON
IGF-1 LR3 vs Standard IGF-1: Research Peptide Comparison
RESEARCH STUDIES
IGF-1 LR3 Research Applications & Published Studies
IGF-1 LR3 research is deeply integrated into cell biology, tissue engineering, and growth factor signaling literature. The following areas represent the most actively investigated applications. All references are to research contexts only.
QUALITY ASSURANCE
Quality & Testing Standards
VivePeptides maintains rigorous quality control for every batch of IGF-1 LR3 peptide. Our commitment to research-grade purity ensures that laboratories receive consistent, reliable compounds for their investigations.
FAQ
Frequently Asked Questions About IGF-1 LR3
What is IGF-1 LR3 used for in research?
IGF-1 LR3 is used in cell biology, tissue engineering, and growth factor signaling research. It is a standard supplement in serum-free cell culture media and is used to study IGF-1R signaling, cell proliferation, myogenesis, and stem cell biology. Its extended half-life makes it preferred over native IGF-1 for in vitro applications. IGF-1 LR3 is sold for research use only.
What purity is VivePeptides IGF-1 LR3?
VivePeptides IGF-1 LR3 is manufactured to ≥99% purity as verified by HPLC analysis. Every batch is tested and verified through independent third-party USA-based laboratories to ensure consistent research-grade quality.
How should IGF-1 LR3 be stored?
Lyophilized IGF-1 LR3 should be stored at -20°C, protected from light and moisture. Once reconstituted, the solution should be stored at 2-8°C and used within 7 days. For longer storage, aliquot and freeze at -20°C. Avoid repeated freeze-thaw cycles.
What is the difference between IGF-1 LR3 and standard IGF-1?
IGF-1 LR3 has two key modifications: an Arg3→Glu substitution and a 13-amino-acid N-terminal extension. These changes dramatically reduce binding to IGF binding proteins (IGFBPs), resulting in a 2-3× increase in potency and a significantly extended half-life in cell culture compared to native IGF-1.
Is VivePeptides IGF-1 LR3 third-party tested?
Yes. Every lot of VivePeptides IGF-1 LR3 undergoes independent third-party testing at USA-based analytical laboratories. Testing includes HPLC purity analysis and mass spectrometry identity confirmation. Results are available upon request for qualified researchers.
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