(5mg + 5mg | Dual GH-Axis Peptide Stack | Pulsatile Growth Hormone Optimization)
CJC-1295 No DAC and Ipamorelin is one of the most researched GH combinations out there. Two different mechanisms, same goal, cleaner, stronger, more natural GH pulses that actually work with your body instead of against it.
🧬 What Is CJC-1295 No DAC + Ipamorelin?
CJC-1295 No DAC (5mg) Also known as Mod GRF 1-29. Short half life of 30 minutes to 2 hours. Stimulates GHRH receptors on the pituitary to trigger GH release in a pulsatile natural pattern. No sustained elevation, just clean spikes that mimic what your body already does.
⚠️ Important: Make sure the product is specifically labeled "CJC-1295 No DAC" or "Mod GRF 1-29." The DAC version has a completely different half-life (6-8 days vs 30 minutes) and is NOT interchangeable in this protocol.
Ipamorelin (5mg) Selective ghrelin receptor agonist. Triggers GH release without touching cortisol, ACTH, or prolactin. One of the cleanest GH secretagogues available.
Why stack them?
CJC-1295 No DAC hits the GHRH receptor. Ipamorelin hits the ghrelin receptor. Two completely different pathways producing a synergistic GH spike that neither compound achieves alone.
Worth knowing: No clinical trials have directly validated this specific combination, the individual peptides are well studied, but the combined protocol itself is based on mechanism logic and widespread community use, not a dedicated trial.
📦 Product — Paramount Peptides
• CJC-1295 No DAC + Ipamorelin (5mg + 5mg)
10mg total, 5mg CJC + 5mg Ipamorelin blended in one vial
99%+ purity
👉 Use code BHGUIDE for a discount
Blended vs separate vials: If you're new to this stack, separate vials let you test tolerance to each peptide individually before combining. Blended vials are more convenient once you know how you respond, but they limit your ability to adjust one dose without changing the other.
🧪 What You'll Need
• CJC-1295 No DAC + Ipamorelin vial • Bacteriostatic Water
Alcohol pads
U-100 insulin syringes (29 to 31 gauge)
Sharps disposal container • Peptide Dosage Calculator
💉 How to Reconstitute
Step Instructions Notes Let vial warm up 15 to 20 minutes room temp Protects peptide integrity Sanitize Wipe stopper with alcohol swab Let air dry before injecting Add BAC Water Inject slowly down the glass wall Never blast directly onto powder Dissolve Swirl gently until clear Never shake Store Refrigerate 2 to 8C Use within 30 days
Solution should be completely clear. Discard if cloudy or has particles.
📐 Reconstitution Math (Corrected)
Formula How to Use Example Concentration (per peptide) Amount of each peptide divided by mL of BAC water 5mg divided by 1mL = 5mg/mL each Dose volume Desired mcg divided by mcg/mL 250mcg divided by 5,000 = 0.05mL Syringe units 100 units = 1mL 5 units = 250mcg of each peptide
Quick math with 1mL BAC water: Each peptide sits at 5mg/mL individually (not 10mg/mL combined, that's the total of both). 5 units on a U-100 syringe = 250mcg of each peptide in one shot.
📊 Dosing Protocols (Corrected)
Goal Dose (each peptide) Units to Draw Frequency Timing General health 200-250mcg 4-5 units Once daily Before bed fasted Enhanced GH pulsatility 100-150mcg 2-3 units Twice daily AM fasted + before bed Performance 250mcg 5 units Once daily Before bed fasted Recovery 300mcg 6 units Once daily Before bed fasted Conservative start 150-200mcg 3-4 units 5 days on 2 days off Before bed fasted
Start conservative: Begin at 200mcg each to assess individual tolerance before pushing to higher protocols.
Timing matters: Always inject fasted. Wait at least 2 to 3 hours after your last meal. Insulin blunts the GH response so eating close to your dose kills the effectiveness.
Once vs twice daily: Once daily before bed works well for most people and lines up with your body's natural overnight GH pulse. Twice daily at lower doses adds a second pulse in the morning fasted and better mimics natural pulsatility. The ghrelin receptor needs about 6 hours to resensitize between doses so don't push more than twice daily.
💉 Injection Guide
Category Details Gauge 29 to 31G Length Half inch SubQ Type U-100 insulin syringe
Injection sites: Abdomen, thigh, upper arm, rotate every 48 to 72 hours to avoid tissue buildup.
SubQ technique: Pinch skin, 45 degree angle, slow inject, withdraw.
⏱️ What to Expect
Timeline What People Report Week 1-2 Improved sleep depth and quality, some report more vivid dreams Week 3-4 Enhanced recovery from exercise, reduced muscle soreness, improved energy Week 6-8 Gradual body composition changes, improved skin quality Week 8-12 Optimized benefits if protocol is dialed in, individual response varies significantly Post-cycle Some benefits may persist for several weeks due to improved sleep and recovery patterns
🔄 Cycle Structure
8 to 12 weeks on, 4 weeks off minimum. The break preserves receptor sensitivity and keeps your natural GH production from getting lazy.
⚠️ Side Effects
Side Effect Notes Water retention Common early on as GH rises Joint discomfort Usually temporary Headache Occasional Numbness or tingling in hands Potential carpal tunnel at higher doses Blood glucose changes Monitor if diabetic Injection site irritation Rotate sites to prevent this
Stop if you notice: Persistent joint pain or swelling that may indicate fluid retention, significant blood glucose changes, unusual fatigue or mood changes that worsen over time, injection site reactions or infections, numbness/tingling in hands or feet, or any signs of accelerated tumor growth if you have a cancer history.
Safety notes:
Use only pharmaceutical-grade peptides with verified Certificates of Analysis, for blends specifically, the COA should show individual peptide purities, not just one combined number
Discontinue if adverse reactions occur, and consider testing peptides separately to identify the source
Regular bloodwork recommended to monitor IGF-1 levels and overall health markers
Rotate injection sites to prevent tissue damage
🚫 What NOT to Stack With This
Compound Notes Synthetic HGH Don't combine, redundant mechanisms may cause excessive GH levels and suppress natural pulsatile release MK-677 Both affect GH pathways, monitor for excessive GH elevation and insulin sensitivity changes with combined use Corticosteroids Can blunt GH response, may require higher doses or alternative timing Thyroid medications Space 4+ hours apart due to potential absorption and metabolic interactions Insulin Growth hormone affects insulin sensitivity, diabetic users need blood glucose monitoring and potential dose adjustments
Compatible stacks: BPC-157 (no known interaction, different mechanisms, GH optimization vs direct tissue repair signaling), TB-500, NAD+, MOTS-C, GLP compounds
🔍 Quick Reference (Corrected)
Detail Info Total vial content 10mg combined (5mg CJC + 5mg Ipamorelin) BAC water to add 1mL Concentration (each peptide) 5mg/mL Starting dose 4-5 units = 200-250mcg each Frequency Once daily before bed or twice daily at lower dose Cycle 8 to 12 weeks on, 4 weeks off Storage Refrigerated 2 to 8C, up to 30 days after reconstitution
🔗 Quick Links
• Paramount Peptides • Bacteriostatic Water • Peptide Dosage Calculator
⚠️ For research and educational purposes only. Not medical advice. Not for human consumption.