Cat-Nr. 100-349-L250
Size 250 μg
€1,912.00
Quantity
Description / human Myostatin-Propeptide protein
Mature Myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin Propeptide exhibits high binding affinity for myostatin and has been shown to be a potent inhibitor of Myostatin. Over-expression of myostatin propeptide in mice resulted in large increases (up to 200%) in skeletal muscle mass, similar to those observed in Myostatin knockout mice. Recombinant Human Myostatin Propeptide is a 27.8 kDa protein consisting of 244 amino acid residues.
More Information
Size 250 μg Source E. coli Biological Activity Determined by its ability to neutralize the Myostatin inhibitory effect of murine MPC-11 cells. The expected ED50 is 0.01–0.04 μg/ml in the presence of 50 ng/ml Myostatin. Purity Confirmation > 98% by SDS-PAGE & HPLC analyses Endotoxin < 0.1 ng/μg of protein (< 1 EU/μg) Length [aa] 244 Molecular Weight 27.8 kDa Species Reactivity Mouse Formulation lyophilized Protein Sequence MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LEVKVTDTPK RSRR Synonyms MSTN; GDF8; MSLHP Uniprot ID O14793 Protein RefSeq NP_005250.1 mRNA RefSeq NM_005259.2
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