Tesamorelin (10 mg Vial) Dosage Protocol
Tesamorelin Dosage Chart
Tesamorelin is dosed at 1 mg–2 mg daily by subcutaneous injection in educational protocols, typically at night. A 10 mg vial reconstituted with bacteriostatic water yields about 3.33 mg/mL. This information is for research and educational use only.
Reconstitute: Add 3.0 mL bacteriostatic water per 10 mg vial → ~3.33 mg/mL concentration.
Standard daily dose: 2 mg (2000 mcg) once daily subcutaneously (FDA-approved protocol).
Easy measuring: At 3.33 mg/mL, 1 unit = 0.01 mL ≈ 33.3 mcg on a U-100 insulin syringe.
Storage: Lyophilized: refrigerate at 2–8 °C (35.6–46.4 °F); reconstituted: refrigerate and use within 7 days with bacteriostatic water.
Tesamorelin is a synthetic 44-amino-acid peptide analog of Growth Hormone-Releasing Hormone (GHRH)[1]. It stimulates endogenous growth hormone release and raises IGF-1 levels, leading to enhanced lipolysis and metabolic benefits[2]. Tesamorelin is FDA-approved for reducing visceral adipose tissue in HIV-associated lipodystrophy and is studied for metabolic disorders and aging research[3][4].
Research context: For evidence on mechanisms, human and preclinical research, limitations, and safety, read Tesamorelin Peptide: Benefits, Uses, Side Effects, Dosage, and Research.
Standard FDA-Approved Protocol (3.0 mL = ~3.33 mg/mL)
Week 1
1 mg / 1000 mcg
30 units (0.30 mL)
Weeks 2–12+
2 mg / 2000 mcg
60 units (0.60 mL)
Frequency: Inject once daily subcutaneously, preferably in the evening to coincide with nocturnal GH release[5][6]. The 2 mg daily dose is the standard FDA-approved regimen for HIV lipodystrophy[7][8]. A one-week titration at 1 mg may improve tolerability before advancing to the full 2 mg dose.
Reconstitution Steps
Draw 3.0 mL bacteriostatic water with a sterile syringe.
Inject slowly down the vial wall; avoid foaming.
Gently swirl until dissolved (do not shake).
Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.
Use within 7 days when reconstituted with bacteriostatic water[1].
Supplies Needed
Plan based on an 8–16 week daily protocol at the standard 2 mg dose (after Week 1 titration).
Peptide Vials (Tesamorelin, 10 mg each):
8 weeks ≈ 11 vials (105 mg total)
12 weeks ≈ 17 vials (161 mg total)
16 weeks ≈ 22 vials (217 mg total)
Insulin Syringes (U-100, 1 mL capacity):
Per week: 7 syringes (1/day)
8 weeks: 56 syringes
12 weeks: 84 syringes
16 weeks: 112 syringes
Bacteriostatic Water (10 mL bottles): Use 3.0 mL per vial for reconstitution.
8 weeks (11 vials): 33 mL → 4 × 10 mL bottles
12 weeks (17 vials): 51 mL → 6 × 10 mL bottles
16 weeks (22 vials): 66 mL → 7 × 10 mL bottles
Alcohol Swabs: One for the vial stopper + one for the injection site each day.
Per week: 14 swabs (2/day)
8 weeks: 112 swabs → recommend 2 × 100-count boxes
12 weeks: 168 swabs → recommend 2 × 100-count boxes
16 weeks: 224 swabs → recommend 3 × 100-count boxes