Recovery research fieldbook Evidence, not treatment advice
Recovery archive

Published recovery field note

Insulin-like Growth Factor I (IGF-1) | Recombinant Proteins

Insulin-like growth factors (IGFs) function as both tissue growth factors and circulating hormones. They actively participate in mammalian development and growth. The IGF family is comprised of insulin and two factors similar to insulin termed IGF-1 and IGF-2. IGF-I and IGF-II are single-chain polypeptides and evolutionarily conserved. The two molecules have 62% homology in their amino acid sequences and their structures resemble the structure of proinsulin. IGFs need a complex system to act, often, it is known as the IGF “axis” system, which should include two IGFs type as IGF-I and IGF-II, two cell-surface receptors such as IGF-receptor type 1 (IGF-1R) and IGF-receptor type 2 (IGF-2R), specific to each IGFs type with tyrosine kinase activity and a family of IGF binding proteins (IGFBPs) . IGFs play an important role in regulating cell proliferation, differentiation, apoptosis, and transformation. Insulin-like Growth Factor I (IGF-1) Recombinant Proteins (17) Cat. No. 상품명 / Synonyms S

Context first

Study findings do not automatically establish clinical benefit, safety, dosing, or suitability for an individual.

Insulin-like growth factors (IGFs) function as both tissue growth factors and circulating hormones. They actively participate in mammalian development and growth. The IGF family is comprised of insulin and two factors similar to insulin termed IGF-1 and IGF-2. IGF-I and IGF-II are single-chain polypeptides and evolutionarily conserved. The two molecules have 62% homology in their amino acid sequences and their structures resemble the structure of proinsulin. IGFs need a complex system to act, often, it is known as the IGF “axis” system, which should include two IGFs type as IGF-I and IGF-II, two cell-surface receptors such as IGF-receptor type 1 (IGF-1R) and IGF-receptor type 2 (IGF-2R), specific to each IGFs type with tyrosine kinase activity and a family of IGF binding proteins (IGFBPs) . IGFs play an important role in regulating cell proliferation, differentiation, apoptosis, and transformation.

Insulin-like Growth Factor I (IGF-1) Recombinant Proteins (17)

Cat. No. 상품명 / Synonyms Species Source Image

HY-P7018

IGF-I/IGF-1 Protein, Human (70a.a)

rHuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I Human E. coli IGF-I/IGF-1 Protein is an insulin-like growth factor that possesses both growth-promoting and metabolic-regulating functions. IGF-I/IGF-1 Protein is also a neurotrophic factor with neuroprotective and neuroplasticity-regulating activities. IGF-I/IGF-1 Protein plays a key role in growth and development, cell proliferation, metabolic regulation and other aspects. IGF-I/IGF-1 protein, Human (70a.a) is a recombinant IGF-I/IGF-1 protein expressed by E. coli without a tag.

(7)

HY-P70783

LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R)

Long R3 IGF-I; Insulin-like growth factor I; MGF; Somatomedin-C; IBP1 Human E. coli The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) is the recombinant human-derived LR3 IGF-I/IGF-1 protein, expressed by E. coli , with tag free and E51R mutation.

(2)

HY-P7203

IGF-I/IGF-1 Protein, Rat

rRtIGF-I; Somatomedin C; IGF1; Mechano growth factor Rat E. coli IGF-I/IGF-1 Protein, Rat has somatomedin activity and ability to potently promote neuronal survival.

(2)

HY-P7070

IGF-I/IGF-1 Protein, Mouse

rMuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I Mouse E. coli IGF-I/IGF-1 Protein is an insulin-like growth factor that possesses both growth-promoting and metabolic-regulating functions. IGF-I/IGF-1 Protein is also a neurotrophic factor with neuroprotective and neuroplasticity-regulating activities. IGF-I/IGF-1 Protein plays a key role in growth and development, cell proliferation, metabolic regulation and other aspects. IGF-I/IGF-1 Protein, Mouse is a recombinant IGF-I/IGF-1 protein expressed by E. coli without a tag.

(8)

HY-P70783G

GMP LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R)

Long R3 IGF-I; Insulin-like growth factor I; MGF; Somatomedin-C; IBP1 Human E. coli The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. GMP LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) is the recombinant human-derived LR3 IGF-I/IGF-1 protein, expressed by E. coli , with tag free.

HY-P73136

IGF-I/IGF-1 Protein, Human (HEK293, hFc)

Insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1 Human HEK293 The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (HEK293, hFc) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P70788

IGF-I/IGF-1 Protein, Human (G49-A118)

Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1 Human E. coli The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (G49-A118) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by E. coli , with tag free.

(2)

HY-P700093AF

Animal-Free IGF-I/IGF-1 Protein, Human (His)

Somatamedin C; IGF-IA; Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1 Human E. coli The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. Animal-Free IGF-I/IGF-1 Protein, Human (His) is the recombinant human-derived animal-FreeIGF-I/IGF-1 protein, expressed by E. coli , with C-His labeled tag.This product is for cell culture use only.

HY-P700478

IGF-I/IGF-1 Protein, Human (P. pastoris, N-His)

Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1 Human P. pastoris The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (P. pastoris, N-His) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by P. pastoris , with N-6*His labeled tag.

(1)

HY-P701241

IGF-I Protein, Salmon

IGF1; IGF-1; insulin-like growth factor 1; Insulin-like growth factor I; Somatomedin C; somatomedin-C Others E. coli IGF-I protein is similar to insulin and exerts effective growth-promoting activity as a ligand of IGF1R. Binding to the α subunit of IGF1R activates intrinsic tyrosine kinase, triggering autophosphorylation of the β subunit. IGF-I Protein, Salmon is the recombinant IGF-I protein, expressed by E. coli , with tag free.

HY-P70698

IGF-I/IGF-1 Protein, Mouse (His)

IGF1; IGF-1; insulin-like growth factor 1; Insulin-like growth factor I; Somatomedin C; somatomedin-C Mouse E. coli IGF-I/IGF-1 Protein, Mouse (His) is a mitogenic cytokine, binds to IGF type 1 receptor, and modulates growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle, endothelium, and bone. IGF1 also mediates neuroprotective mechanism.

(1)

HY-P70698A

IGF-I/IGF-1 Protein, Mouse (N-His)

IGF1; IGF-1; insulin-like growth factor 1; Insulin-like growth factor I; Somatomedin C; somatomedin-C Mouse E. coli The IGF-I/IGF-1 protein is structurally similar to insulin and has potent growth-promoting activity. As a physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts, exceeding the efficacy of insulin at lower concentrations. IGF-I/IGF-1 Protein, Mouse (N-His) is the recombinant mouse-derived IGF-I/IGF-1 protein, expressed by E. coli , with N-6*His labeled tag.

(2)

HY-P70698AF

Animal-Free IGF-I/IGF-1 Protein, Mouse (His)

rMuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I Mouse E. coli The IGF-I/IGF-1 protein is structurally similar to insulin and has potent growth-promoting activity. As a physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts, exceeding the efficacy of insulin at lower concentrations. Animal-Free IGF-I/IGF-1 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIGF-I/IGF-1 protein, expressed by E. coli , with C-His labeled tag.This product is for cell culture use only.

HY-P7018A

DES1-3 IGF-I/IGF-1 Protein, Human

rHuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I Human E. coli

(2)

HY-P74843

IGF-I/IGF-1 Protein, Mouse (P.pastoris)

Insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1 Mouse P. pastoris IGF-I/IGF-1 Protein, part of the insulin family, is highlighted. IGF-I/IGF-1 Protein, Mouse (P.pastoris) is the recombinant mouse-derived IGF-I/IGF-1 protein, expressed by P. pastoris , with tag free.

HY-P700241AF

Animal-Free IGF-I Protein, Pig (His)

Insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1 Pig E. coli The IGF-I protein is structurally similar to insulin and has excellent growth-promoting activity. As a potential physiological regulator, it affects [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Animal-Free IGF-I Protein, Pig (His) is the recombinant pig-derived animal-FreeIGF-I protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

HY-P706010

IGF-I/IGF-1 protein, Rat (GST)

Igf1; Igf-1Insulin-like growth factor I; IGF-I; Somatomedin Rat E. coli

Connected topics

Follow this recovery question