GHRH Analog • Growth Hormone Support
Stimulate Natural Growth Hormone Production
CJC-1295 (no DAC) is a growth hormone-releasing hormone (GHRH) analog that stimulates your pituitary gland to naturally produce more growth hormone. Unlike synthetic HGH, it works with your body’s own rhythms to support recovery, body composition, and vitality. Join our waitlist to be notified when available.
2-10x
GH Level Increase*
1.5-3x
IGF-1 Elevation*
~30
Minute Half-Life
1-3x
Daily Dosing GHRH Analog
5mg
5mg per vial
Stimulates natural GH production
Preserves pulsatile release pattern
Short half-life (~30 min)
Often paired with Ipamorelin
Ideal For
Adults seeking to optimize growth hormone levels naturally for improved recovery, body composition, sleep quality, and overall vitality. Schedule Consultation
The Science
What is CJC-1295 No DAC?
CJC-1295 (no DAC), also known as Modified GRF (1-29) or Mod GRF, is a synthetic analog of growth hormone-releasing hormone (GHRH). It signals your pituitary gland to produce and release more growth hormone naturally, rather than introducing synthetic HGH from outside the body.
The “no DAC” version has a short half-life of approximately 30 minutes, which preserves the body’s natural pulsatile pattern of GH release. This is important because growth hormone is normally released in pulses, not continuously—and maintaining this rhythm may reduce the risk of receptor desensitization.
Clinical studies showed that GHRH analogs like CJC-1295 can increase GH levels by 2-10 fold and IGF-1 levels by 1.5-3 fold. It’s often combined with a growth hormone secretagogue like Ipamorelin for synergistic effects—the GHRH analog amplifies the signal while the secretagogue triggers the release. Schedule Consultation
GHRH Receptor Activation
Binds to GHRH receptors on pituitary somatotroph cells, signaling them to synthesize and release growth hormone into circulation.
Pulsatile GH Release
The short half-life (~30 min) allows GH to be released in natural pulses rather than sustained elevation, preserving physiologic rhythm.
IGF-1 Production
Elevated GH stimulates the liver to produce IGF-1, which mediates many of growth hormone’s anabolic and regenerative effects throughout the body.
Learn If You’re a Candidate
Half-Life
~30 minutes
6-8 days
GH Release Pattern
Pulsatile (natural)
Sustained elevation
Dosing Frequency
1-3x daily
1-2x weekly
Receptor Desensitization
Lower risk
Higher risk
Dose Adjustability
Easy to titrate
Harder to adjust
*Individual responses vary. Consult with our physicians to determine the best approach for your goals.
Discuss Your Options
Natural GH Stimulation
Signals your pituitary to produce its own growth hormone rather than introducing synthetic HGH—working with your body’s natural systems.
Improved Recovery
Enhanced GH and IGF-1 levels support tissue repair, muscle recovery after exercise, and overall healing processes.
Body Composition
Growth hormone optimization may support increased lean muscle mass and reduced body fat when combined with proper nutrition and exercise.
Better Sleep Quality
GH is naturally released during deep sleep. Optimizing GH levels may support more restorative sleep cycles and overall sleep quality.
Synergy with Secretagogues
Often combined with Ipamorelin or other GH secretagogues for enhanced effects—the GHRH analog amplifies what the secretagogue triggers.
Anti-Aging Support
GH and IGF-1 decline with age. Restoring more youthful levels may support skin health, energy, cognitive function, and overall vitality.
Start Your Journey
Consultation
Meet with our physician to discuss your goals, review health history, and determine if peptide therapy is appropriate for you.
Lab Work
Baseline testing including IGF-1, metabolic panel, and other relevant markers to assess your current hormone status.
Protocol Design
Your physician designs a personalized protocol—often combining CJC-1295 with Ipamorelin—tailored to your specific needs and goals.
Ongoing Optimization
Regular follow-ups to monitor progress, adjust dosing as needed, and ensure you’re achieving optimal results safely.
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Safety & Candidacy
Is CJC-1295 Right for You?
CJC-1295 therapy requires proper medical evaluation and monitoring. Our physicians will assess whether you’re a good candidate based on your health history and goals.
Clinical research — Studies show 2-10x GH elevation and 1.5-3x IGF-1 increase in healthy adults Physician oversight — Requires proper evaluation, baseline labs, and ongoing monitoring Common effects — May include flushing, headache, or injection site reactions Not for everyone — Contraindicated in active cancer, certain medical conditions Speak With a Physician
GHRH
Analog that stimulates your body’s own growth hormone production
~30 min
Short half-life preserves natural pulsatile GH release pattern
CJC-1295 without DAC (also called Mod GRF 1-29) has a short half-life of about 30 minutes, allowing for pulsatile GH release that mimics the body’s natural pattern. CJC-1295 with DAC has a half-life of 6-8 days, causing sustained GH elevation. Most practitioners prefer the “no DAC” version because it’s more physiologic and allows easier dose adjustment.
CJC-1295 stimulates your pituitary gland to produce its own growth hormone, while synthetic HGH (somatropin) introduces external growth hormone directly. The GHRH analog approach is considered more physiologic because it works through your body’s natural feedback systems and preserves pulsatile release patterns.
CJC-1295 (a GHRH analog) and Ipamorelin (a growth hormone secretagogue) work through different mechanisms that complement each other. The GHRH analog amplifies the GH-releasing signal, while the secretagogue triggers the actual release. Together, they can produce greater GH elevation than either alone—this is called synergy.
Due to its short half-life, CJC-1295 no DAC is typically administered 1-3 times daily via subcutaneous injection. Common protocols include dosing before bed (to enhance natural nighttime GH release) or pre-workout. Your physician will design a protocol specific to your goals.
Results vary by individual, but potential benefits include improved recovery from exercise, better sleep quality, positive changes in body composition (more lean mass, less fat), improved skin quality, and enhanced overall vitality. Clinical studies showed 2-10x increases in GH levels and 1.5-3x increases in IGF-1. Results typically develop over weeks to months of consistent use.
Common side effects may include flushing, headache, dizziness, nausea, and injection site reactions. These are typically mild and transient. Because GH can affect blood sugar and other metabolic parameters, proper medical supervision and monitoring are essential.
CJC-1295 is not appropriate for individuals with active cancer or history of certain cancers (GH can promote cell growth), pregnant or nursing women, or those with certain pituitary conditions. A thorough medical evaluation is required before starting therapy. Our physicians will review your complete health history to determine if you’re a candidate.
Get Started Today
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Optimize Your Growth Hormone
Schedule a consultation with our medical team to learn if CJC-1295 peptide therapy is right for your health and wellness goals.
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Or call us directly: +1 213-325-3373
*CJC-1295 is a research peptide used in clinical settings for growth hormone optimization. The statistics cited (2-10x GH increase, 1.5-3x IGF-1 increase) are from published clinical studies. Individual results vary. CJC-1295 therapy requires physician evaluation, baseline laboratory testing, and ongoing monitoring. It is not appropriate for individuals with active cancer, certain pituitary conditions, or other contraindications. This therapy should only be undertaken under proper medical supervision. Consult with our medical team to determine if you are a candidate.
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