Thymosin beta-4 promotes cell migration and angiogenesis in multiple injury models. The synthetic 'TB-500' fragment is assumed to behave similarly but has less direct study.
0 human studies · 15 animal studies
Increases endothelial cell migration and tubule formation in vitro.
Speeds dermal wound closure by roughly 40% in rodent full-thickness models.
Tendon fibroblast migration enhanced at low micromolar concentrations.
Top citations
Goldstein 2012 — Mechanistic review
Malinda 1999 — Wound healing model
Our take
Mechanistically credible. Most user reports describe weeks-to-months timelines for tendinopathies, not the day-scale claims you'll see on forums.