IGF-1 LR3 (1 mg Vial) Dosage Protocol
IGF-1 LR3 Dosage Chart
IGF-1 LR3 is dosed at 20 mcg–50 mcg daily via subcutaneous injection in educational protocols. A 1 mg vial reconstituted with bacteriostatic water yields about 0.333 mg/mL. This information is for research and educational use only.
Reconstitute: Add 3.0 mL bacteriostatic water → ~0.333 mg/mL concentration (333 mcg/mL).
Typical daily range: 20–50 mcg once daily subcutaneously (gradual titration recommended).
Easy measuring: At 0.333 mg/mL, 1 unit = 0.01 mL ≈ 3.33 mcg on a U-100 insulin syringe.
Storage: Lyophilized: freeze at −20 °C (−4 °F) for up to 12 months; after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F) and use within 30 days; avoid repeated freeze–thaw cycles.
IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is a modified analog of human IGF-1 with significantly extended half-life, studied for its anabolic and metabolic effects[1]. This synthetic variant exhibits reduced binding to IGF binding proteins, allowing enhanced bioavailability and systemic activity[2]. This educational protocol presents a once-daily subcutaneous approach with conservative titration for research applications.
Research context: For evidence on mechanisms, human and preclinical research, limitations, and safety, read IGF-1 LR3 Peptide: Benefits, Uses, Side Effects, Dosage, and Research.
Standard / Gradual Approach (3 mL = ~0.333 mg/mL)
Weeks 1–2
20 mcg (0.02 mg)
6 units (0.06 mL)
Weeks 3–4
40 mcg (0.04 mg)
12 units (0.12 mL)
Weeks 5–8
50 mcg (0.05 mg)
15 units (0.15 mL)
Frequency: Inject once daily subcutaneously, typically in the morning or post-workout with food intake to mitigate insulin-like effects on blood glucose[3]. This schedule uses the maximum practical dilution (3.0 mL) for clear measurements. For ≤10-unit (≤0.10 mL) administrations, consider 30- or 50-unit insulin syringes for improved readability.
Reconstitution Steps
Draw 3.0 mL bacteriostatic water with a sterile syringe.
Inject slowly down the vial wall to avoid foaming; do not shake.
Gently swirl or roll until the lyophilized powder dissolves completely into a clear solution.
Label the vial with reconstitution date and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.
Use within 30 days of reconstitution; for longer storage, prepare aliquots and freeze at −20 °C (−4 °F) for up to 3–6 months[4].
Supplies Needed
Plan based on an 8–16 week daily protocol with gradual titration.
Peptide Vials (IGF-1 LR3, 1 mg each):
8 weeks ≈ 3 vials (~2.24 mg total needed)
12 weeks ≈ 4 vials (~3.64 mg total needed)
16 weeks ≈ 6 vials (~5.04 mg total needed)
Insulin Syringes (U-100, 0.5 mL or 1 mL):
Per week: 7 syringes (1/day)
8 weeks: 56 syringes
12 weeks: 84 syringes
16 weeks: 112 syringes
Bacteriostatic Water (10 mL bottles): Use 3.0 mL per vial for reconstitution.
8 weeks (3 vials): 9 mL → 1 × 10 mL bottle
12 weeks (4 vials): 12 mL → 2 × 10 mL bottles
16 weeks (6 vials): 18 mL → 2 × 10 mL bottles
Alcohol Swabs: One for the vial stopper + one for the injection site each day.
Per week: 14 swabs (2/day)
8 weeks: 112 swabs → recommend 2 × 100-count boxes
12 weeks: 168 swabs → recommend 2 × 100-count boxes
16 weeks: 224 swabs → recommend 3 × 100-count boxes