CosMyc 01 (Canine Oncology Study of Myc inhibition: Pharmacokinetics and short-term tolerability of a novel peptide myc inhibitor in dogs with cancer) Currently Enrolling
Summary of Study: The MYC gene plays a role in many types of cancer. However, this gene and its effects were once thought to be impossible to target with therapy. Recent advances have changed this paradigm and made this a viable target for therapy. The purpose of this study is to determine if a novel Study Details
Study of Local Administration of Hemostatic Gel in Canine Epistaxis (SOLACE) Open
Summary of Study: The trial aims to evaluate the tolerability and adverse event profile of hemostatic gel in the setting of canine epistaxis of any cause. With this, we also are studying the potential hemostatic activity of hemostatic gel in canine epistaxis. Canine epistaxis was found to be a result from a variety of causes, including trauma, foreign bodies, infections, coagulopathies, Study Details
Stratification of Outcomes for Lymphoma In Dogs with Relapsed Lymphoma (SOLID-Relapse) Open
Summary of Study: The Stratification of Outcomes for Lymphoma In Dogs with Relapsed Lymphoma (SOLID-Relapse) study is a clinical trial focused on the follow- up of dogs previously enrolled in Ethos-SOLID. This population of relapsed patients will add the perspective of longitudinal analysis and provide a unique opportunity to study the role of functional precision medicine in treatment of relapsed lymphoma. Study Details
Biobanking Osteosarcoma as a Nexus for Evaluation and Staging (BONES) Open
Advancing bone cancer research in dogs through Osteosarcoma Summary of Study Osteosarcoma is the most prevalent form of bone cancer in dogs, sharing many biological similarities with the disease in humans. Unfortunately, even when a tumor is completely removed through surgery, over 90% of dogs eventually die because the cancer spreads to their lungs. The Study Details
Clinical Study for Dogs with Chronic Enteropathy Open
Clinical Study: Diet and probiotic therapy for chronic enteropathy in dogs Currently Enrolling Comparison of diet and probiotic vs. diet alone to control clinical signs of chronic enteropathy and diarrhea in dogs Study Goals: This study aims to evaluate a new probiotic-based therapeutic for chronic enteropathy and chronic diarrhea in dogs. Targeted alteration of the Study Details
Evaluation of use of vessel sealing device during elective castration surgeries for exotic companion mammals Open
Study on vessel sealing devices in elective spay/neuter operations for exotic pets Summary of Study: Spay and neuter procedures are surgeries recommended for and performed on most exotics companion mammals for population control, to prevent reproductive diseases including cancer, and to help reduce behavioral concerns. Evaluation of surgical techniques is of great importance to these Study Details
Minimally Invasive Metastasectomy in Canines (MIMIC) Open
Minimally-invasive surgical bone cancer treatment for dogs CURRENTLY ENROLLING The MIMIC clinical trial is open for enrollment. Ethos Discovery is investigating a new minimally-invasive surgical treatment for canine osteosarcoma that has metastasized, or spread, to the lungs. This study is subsidized and all procedures will be provided at an affordable, low cost. Eligibility Criteria: • Study Details
TIDBITS: Biomarkers for Response to Immunosuppression in Immune-Mediated Thrombocytopenia Open
TIDBITS: Bio-markers for Immune-Mediated Thrombocytopenia and response to immunosuppression in dogs Goal: Investigate whether exosome RNA profiles in ITP differ in treatment of naive dogs compared to those that respond with immunosuppression Inclusion Criteria: Canine patients with platelet count < 40K Clinical evidence of bleeding Weight ≥ 2kg Ability to administer vincristine No other causes Study Details
Probiotic Study in Dogs Open
We are studying a novel live probiotic product typically found in the gut of healthy dogs to evaluate the ability of this probiotic to resolve diarrhea in dogs. Study Details
Biomarkers for Hemorrhages Associated with Slipped Discs in French Bulldogs Open
We are collecting blood samples from eligible French Bulldogs to research biomarkers associated with hemorrhages (bleeding) in French bulldogs. Study Details
Novel Treatment for Hemorrhages Associated with Slipped Discs in French Bulldogs Open
Ethos Discovery seeks to investigate a new approach to reducing hemorrhages (bleeding) in French Bulldogs following slipped discs in their back. Study Details
Ethos Precision Medicine Umbrella Study for Hemangiosarcoma (ePUSH) Open
Is your dog undergoing surgery for a ruptured splenic tumor? Ethos Discovery would love to have you and your dog participate in our clinical trial! We are evaluating drugs for the treatment of HSA with the goal of curing this aggressive cancer. Study Details