Sermorelin (10 mg Vial) Dosage Protocol
Sermorelin Dosage Chart
Sermorelin is dosed at 200 mcg–500 mcg daily via subcutaneous injection in educational protocols. A 10 mg vial reconstituted with bacteriostatic water yields about 3.33 mg/mL. This information is for research and educational use only.
Reconstitute: Add 3.0 mL bacteriostatic water → ~3.33 mg/mL concentration.
Typical daily range: 200–500 μg once daily at bedtime (gradual titration).
Easy measuring: At 3.33 mg/mL, 1 unit = 0.01 mL ≈ 33.3 μg on a U‐100 insulin syringe.
Storage: Lyophilized: refrigerate at 2–8 °C (36–46 °F); after reconstitution, refrigerate at 2–8 °C (36–46 °F) and use within 10–14 days[4].
Sermorelin is a synthetic growth hormone–releasing hormone (GHRH) analog that stimulates endogenous pituitary GH secretion[1]. Originally approved for pediatric growth hormone deficiency, it is studied for adult off‐label use to support physiologic GH output and IGF‐1 levels[2]. This educational protocol presents a once‐daily subcutaneous approach administered at bedtime to align with natural nocturnal GH release[3].
Research context: For evidence on mechanisms, human and preclinical research, limitations, and safety, read Sermorelin Peptide: Benefits, Uses, Side Effects, Dosage, and Research.
Standard / Gradual Approach (3 mL = ~3.33 mg/mL)
Weeks 1–2
200 μg (0.2 mg)
6 units (0.06 mL)
Weeks 3–4
300 μg (0.3 mg)
9 units (0.09 mL)
Weeks 5–6
400 μg (0.4 mg)
12 units (0.12 mL)
Weeks 7–8
500 μg (0.5 mg)
15 units (0.15 mL)
Frequency: Inject once daily subcutaneously at bedtime. Bedtime administration is strongly recommended because endogenous GH secretion peaks during sleep[3]. This schedule uses the largest practical dilution (3.0 mL) to keep per‐injection units measurable with standard insulin syringes.
For ≤10‐unit (≤0.10 mL) administrations, consider 30‐ or 50‐unit insulin syringes for improved readability.
Reconstitution Steps
Draw 3.0 mL bacteriostatic water with a sterile syringe.
Inject slowly down the vial wall; gently swirl to dissolve (do not shake vigorously)[2].
Label with reconstitution date and refrigerate at 2–8 °C (36–46 °F), protected from light[2][4].
Wipe vial stopper with alcohol before each use; use a new sterile needle and syringe for each injection[2].
Supplies Needed
Plan based on an 8–week daily protocol with gradual titration (56 injections total).
Peptide Vials (Sermorelin, 10 mg each):
8 weeks (total ~19.6 mg consumed): 2 vials (20 mg total)
12 weeks (similar daily range): 4 vials
Tip: Have 1 extra vial as backup in case of spillage or loss.
Insulin Syringes (U‐100):
Per week: 7 syringes (1/day)
8 weeks: 56 syringes (recommend 1 × 100‐count box)
12 weeks: 84 syringes (1 × 100‐count box)
Preferred: 0.3–0.5 mL size with 28G–31G needle, 5/16′′ to 1/2′′ length for subcutaneous use. Consider 30‐ or 50‐unit syringes for low‐dose weeks for improved precision.
Bacteriostatic Water (10 mL bottles): Use ~3.0 mL per vial for reconstitution.
8 weeks (2 vials): 6 mL → 1 × 10 mL bottle
12 weeks (4 vials): 12 mL → 2 × 10 mL bottles
Contains benzyl alcohol preservative; do not use if allergic.
Alcohol Swabs: One for the vial stopper + one for the injection site each day.
Per week: 14 swabs (2/day)
8 weeks: 112 swabs → recommend 2 × 100‐count boxes
12 weeks: 168 swabs → recommend 2 × 100‐count boxes