Sermorelin Dosing Protocol: 10 mg Vial — Extended Cycle Dosing & Supplies
Two-month supply guide for sermorelin using the 10 mg vial — efficient for patients on established 300–500 μg nightly protocols.
Quickstart highlights
Sermorelin GHRH 1-29 NH2 stimulates somatotroph GH release through pituitary GHRH receptor binding.
Concentration: 2 mg/mL (10 mg vial + 5 mL bacteriostatic water).
At 2 mg/mL: 200 μg = 10 units, 300 μg = 15 units, 500 μg = 25 units nightly.
One 10 mg vial provides 33 nightly doses at 300 μg or 20 doses at 500 μg.
Inject 30–60 minutes before sleep; avoid food 2 hours prior.
Refrigerate; use within 28 days of reconstitution.
Dosing table
For educational reference only. Your prescribing provider may adjust doses based on your clinical profile and response.
1-4
200
10
Once daily (before bed)
200 μg — 10 units nightly; 10 mg vial provides 50 nightly doses at this level
5-12
300
15
300 μg — 15 units; ~33 doses per vial
13+
500
25
500 μg — 25 units; ~20 doses per vial (about 3 weeks of nightly dosing)
Your free Sermorelin tracker
Dose reminders
Injection logging
Cycle progress
Reconstitution steps
Draw 5 mL bacteriostatic water into a 10 mL syringe or in two 2.5 mL draws from a 3 mL syringe.
Inject slowly down the vial wall; swirl gently until fully dissolved — do not shake.
Final concentration: 2 mg/mL. At 2 mg/mL: 1 unit (U-100) = 20 μg.
Label with date and concentration (2 mg/mL); refrigerate at 2–8 °C. Use within 28 days.
Supplies needed
12-week plan
1 vial
84 syringes
5 mL bac water
84 alcohol swabs
24-week plan
2 vials
168 syringes
10 mL bac water
168 alcohol swabs
Protocol overview & cycle notes
Provide an extended 12-week supply of sermorelin from a single 10 mg vial for patients at established 300–500 μg nightly maintenance dosing, reducing reconstitution frequency versus the 5 mg vial.
Cycle length: 12 weeks on.
Off-cycle: 4–6 weeks off; check IGF-1 before resuming.
Storage & handling
Injection & tracking tips
Inject subcutaneously 30–60 minutes before sleep for optimal nocturnal GH pulse amplification.
Avoid food for 2 hours before injection; insulinogenic states suppress GH response to sermorelin.
The 10 mg vial at 2 mg/mL requires 5 mL bac water — use two separate draws from a 3 mL syringe or a larger syringe if available.
Tracking
Logging helps you and your provider spot patterns and adjust dose or timing.
Measure IGF-1 at baseline and every 6 weeks to track GH axis response.
Log morning resting heart rate, sleep hours, and subjective energy (0–10) weekly.
Record body composition changes at 8 and 16 weeks.
How this works & references
Sources
Source: Vittone J et al. — Nightly sermorelin 500 μg in GH-deficient adults. J Clin Endocrinol Metab. 1997
Sermorelin: a better approach to management of adult-onset growth hormone insufficiency?. Walker RF et al. — Clin Interv Aging — 2006
Polyethylene glycol-conjugated growth hormone-releasing hormone is long acting and stimulates GH in healthy young and elderly subjects. Munafo A et al. — Eur J Endocrinol — 2005
Frequently asked questions
Related protocols
KLOW Blend Dosing Protocol — BPC-157, TB-500, KPV & GHK-Cu Guide
KLOW peptide blend (BPC-157 + TB-500 + KPV + GHK-Cu) dosing guide for tissue repair, anti-inflammatory support, and extracellular matrix remodeling — the GLOW blend plus KPV.
GLOW Blend Dosing Protocol — BPC-157, TB-500 & GHK-Cu Skin & Repair Guide
GLOW peptide blend (BPC-157 + TB-500 + GHK-Cu) dosing guide for tissue repair, angiogenesis, and collagen and connective-tissue remodeling.
Vilon Dosing Protocol: 20 mg Vial — Dipeptide Immune & Longevity Bioregulator Guide
Vilon (Lys-Glu dipeptide) Russian immune and longevity bioregulator dosing guide — the simplest Khavinson bioregulator for systemic immune normalization and longevity support.
Vesugen Dosing Protocol: 20 mg Vial — Vascular Bioregulator & Cardiovascular Guide
Vesugen (Lys-Glu-Asp tetrapeptide) Russian vascular bioregulator dosing guide — endothelial cell gene normalization for arterial health, blood pressure regulation, and cardiovascular aging.
This content is for informational purposes only and does not constitute medical advice. Consult a licensed healthcare provider before starting any peptide therapy. Dosing and protocols may vary by formulation and prescriber.
Need help?