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IGF-1 LR3 – 1mg Research-Grade Recombinant IGF-1 Analog
IGF-1 LR3 (Long R3 Insulin-Like Growth Factor-1) is a recombinant analog of human IGF-1 engineered with a 13-amino-acid N-terminal extension and an arginine substitution at position 3. These modifications significantly reduce IGF-binding protein (IGFBP) affinity, enhancing receptor accessibility and extending activity in vitro. Mechanistic findings indexed under PMID: 1318405 describe the altered receptor kinetics and potent IGF-1R activation profile associated with LR3 variants.
In controlled laboratory environments, IGF-1 LR3 is utilized to examine IGF-1 receptor signaling, PI3K/Akt and MAPK pathway modulation, cellular proliferation responses, receptor-binding kinetics, and biochemical processes influenced by reduced IGFBP sequestration. Its enhanced potency supports applications in pathway-mapping assays, receptor-stimulation models, and growth factor–dependent biochemical research.
The lyophilized research-grade peptide ensures reproducibility, stability, and consistent purity for laboratory assays requiring reliable IGF-1 analog performance.
Important Information About This Research Product:
Your vials are not empty — the lyophilized material collects at the bottom. All products arrive as lyophilized powder requiring reconstitution. (Bacteriostatic water is not supplied.) Store in a cool, dry environment — short-term at 4°C, long-term at ?20°C. This material is strictly for laboratory research use only — no instructions for reconstitution, dosing, or administration can be provided.
$69.99
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128 in stock
Quantity Quantity Discounts 2 - 9 $66.99 10 - 19 $63.99 20 + $59.99
IGF-1 LR3 - 1mg quantity
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Lyophilized Powder
Lyophilization is defined as a freeze-drying process that removes water from a product after it is frozen and placed under a vacuum.
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Synonyms Appearance CAS # Structure Sequence Molecular Formula Molecular Weight Storage
Long r3 IGF-1, LR3 IGF, IGF1 LR3, Long Arg3 IGF-1
Lyophilized Powder
946870-92-4
MFPAMPLSSLFVNGPRTLCGA ELVDALQFVCGDRGFYFNKPT GYGSSSRRAPQTGIVDECCFR SCDLRRLEMYCAPLKPAKSA
C400H625N111O115S9
9111.0 g/mol
Store all products in a dry, cool, and dark place away from UV rays. For best preservation, store @ 4°C.
Reviews(1)
Rated 5 out of 5
Kellan M
October 17, 2023
I’ve been a loyal customer of Origin Compounds for quite some time now. I’ve never encountered any issues with my orders. It’s a 5 star service from them always.
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* These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not intended to diagnose, treat, cure or prevent any disease.
**All products for sale on this site are intended for laboratory and research use only. They are not intended for human consumption or ingestion.
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