Triple Synergy Peptide Blend
Advanced combination for GH and metabolic support.
Our proprietary triple-blend combines Tesamorelin (10mg), Ipamorelin (5mg), and MOTS-c (10mg) to deliver synergistic growth hormone optimization, visceral fat reduction, and mitochondrial metabolic enhancement—a comprehensive approach to body composition, recovery, and longevity.
3-in-1
Synergistic Blend
25mg
Total Per Vial
Multi
Pathway Activation
22+
BHRC Locations
Tesamorelin
10mg per dose
GHRH pathway activation
Visceral fat reduction
GH pulsatile release
Primary Benefits
Stimulates natural GH production through GHRH receptor activation, with proven visceral adipose tissue reduction and metabolic benefits. Learn More
Ipamorelin
5mg per dose
Ghrelin receptor activation
Selective GH stimulation
Minimal cortisol effects
Primary Benefits
Amplifies GH secretion through ghrelin receptor activation without elevating cortisol or prolactin, enhancing the blend’s effectiveness. Learn More Stack Complete
MOTS-C
10mg per dose
Mitochondrial optimization
Metabolic enhancement
Insulin sensitivity support
Primary Benefits
Enhances cellular energy production, improves metabolic function, and supports exercise response through mitochondrial regulation. Learn More
The Science
What is Tesa/Ipa/MOTS-c?
This advanced peptide blend combines three complementary mechanisms: Tesamorelin—a GHRH analog that stimulates pituitary growth hormone release with proven visceral fat reduction; Ipamorelin—a selective ghrelin mimetic that amplifies GH secretion without cortisol or prolactin elevation; and MOTS-c—a mitochondrial-derived peptide that enhances metabolic efficiency, insulin sensitivity, and cellular energy production.
Together, these peptides create a synergistic cascade: Tesamorelin and Ipamorelin work upstream to optimize endogenous GH pulsatility through distinct but complementary pathways, while MOTS-c enhances downstream metabolic utilization—improving how your body processes nutrients, burns fat, and generates cellular energy.
This triple-action approach targets body composition from multiple angles: GH-mediated lipolysis (especially visceral fat), lean muscle preservation, mitochondrial biogenesis, insulin sensitivity, and recovery enhancement. At BHRC, we use this blend for patients seeking comprehensive metabolic optimization beyond what single peptides can achieve. Book a Consultation
Tesamorelin: GHRH Pathway
Binds to GHRH receptors on pituitary somatotrophs, triggering endogenous growth hormone release while specifically targeting visceral adipose tissue reduction through enhanced lipolysis.
Ipamorelin: Ghrelin Amplification
Selectively activates ghrelin receptors to amplify GH secretion without elevating cortisol or prolactin—providing clean, pulsatile GH release that synergizes with Tesamorelin’s GHRH action.
MOTS-c: Mitochondrial Signaling
Mitochondrial-encoded peptide that translocates to the nucleus, activating AMPK and regulating metabolic gene expression—enhancing insulin sensitivity, glucose metabolism, and cellular energy efficiency.
Learn If You Qualify
Visceral Fat Reduction
Tesamorelin’s proven mechanism specifically targets dangerous visceral adipose tissue while the GH cascade promotes overall lipolysis and improved body composition metrics.
Optimized GH Secretion
Dual GH pathway activation through GHRH and ghrelin receptors creates robust, pulsatile growth hormone release that mimics natural physiological patterns for maximum anabolic benefit.
Metabolic Enhancement
MOTS-c activation of AMPK pathways improves insulin sensitivity, glucose disposal, mitochondrial function, and overall metabolic health—addressing the downstream utilization of nutrients.
Enhanced Recovery
Growth hormone’s anabolic effects combined with improved mitochondrial efficiency accelerate tissue repair, reduce recovery time, and support training adaptation at the cellular level.
Lean Mass Preservation
GH’s protein-sparing effects protect lean muscle tissue during caloric restriction while promoting preferential fat oxidation—ideal for recomposition protocols and cutting phases.
Comprehensive Action
Multi-pathway targeting addresses body composition, metabolic health, energy production, and recovery simultaneously—providing benefits beyond what single-peptide therapy can achieve.
Start Your Journey
Consultation
Meet with our physician to assess your body composition goals, metabolic health, and determine if this peptide blend is appropriate for your needs.
Lab Testing
Comprehensive panels including IGF-1, fasting glucose, insulin, HbA1c, lipids, metabolic markers, and hormone levels to establish baseline health status.
Custom Protocol
Personalized treatment plan with precise dosing schedule, injection training, cycle duration, and nutrition recommendations to maximize synergistic fat loss and metabolic benefits.
Ongoing Care
Regular follow-ups with progress tracking, body composition analysis, lab monitoring, and protocol adjustments to ensure safe, effective results.
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Safety & Candidacy
Research-Backed Triple Blend
This peptide combination leverages well-researched mechanisms: Tesamorelin (FDA-approved for lipodystrophy), Ipamorelin (extensively studied for GH release), and MOTS-c (emerging mitochondrial peptide with metabolic research). While not FDA-approved as a combination therapy for performance or body composition, it’s used in supervised medical protocols for metabolic optimization.
Synergistic pathways — three complementary mechanisms for comprehensive results Proven components — each peptide individually researched and documented Metabolic focus — addresses both GH optimization and cellular energy utilization Medical supervision — requires physician oversight and regular monitoring Speak With a Physician
12-16wks
Typical protocol duration with medical monitoring and planned assessment points
1x/day
Once-daily subcutaneous injection, typically before bed for optimal GH pulsatility
This blend targets body composition and metabolism through complementary pathways. Tesamorelin and Ipamorelin work synergistically to optimize GH release via different receptors (GHRH and ghrelin), while MOTS-c enhances how your cells utilize that GH signal through improved mitochondrial function and insulin sensitivity. This multi-pathway approach delivers more comprehensive results than any single peptide alone.
The blend is administered as a single subcutaneous injection once daily, typically before bed to align with natural GH secretion patterns. Our clinical team provides comprehensive training on reconstitution, injection technique, site rotation, and proper storage. The combined formulation simplifies administration compared to dosing three separate peptides.
Patients typically report noticeable visceral fat reduction within 8-12 weeks, improved body composition metrics, enhanced recovery, better sleep quality, increased energy, and improved metabolic markers including fasting glucose and insulin sensitivity. Lean muscle preservation during caloric restriction is common. Results are maximized when combined with proper nutrition, resistance training, and lifestyle optimization.
Typical protocols range from 12-16 weeks under medical supervision, with ongoing monitoring of body composition, metabolic markers, and IGF-1 levels. Some patients use extended protocols depending on goals and response. Your physician will design a protocol based on your individual needs, lab results, and progress tracking including DEXA scans or other body composition assessments.
Potential side effects include injection site reactions, mild water retention, joint discomfort, or transient changes in glucose metabolism. Some patients experience increased hunger from Ipamorelin’s ghrelin activity. GH-related effects like mild carpal tunnel symptoms are possible but uncommon at therapeutic doses. Regular monitoring including glucose testing is important, especially for those with diabetes or metabolic syndrome.
Ideal candidates are adults seeking comprehensive body recomposition, visceral fat reduction, or metabolic optimization who haven’t achieved desired results with diet and exercise alone. Those with metabolic syndrome, insulin resistance, or age-related GH decline may particularly benefit. Contraindications include active malignancy, uncontrolled diabetes, pregnancy, or pituitary disorders. A physician consultation with comprehensive lab work is required.
Monitoring includes regular body composition analysis (DEXA or similar), fasting glucose and insulin, HbA1c, IGF-1 levels, lipid panels, and clinical assessments. We track both objective metrics (visceral fat area, lean mass, metabolic markers) and subjective outcomes (energy, recovery, sleep). Your physician schedules follow-ups every 4-6 weeks during active therapy to ensure safety and optimize results.
Get Started Today
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Begin Your Transformation
Schedule a consultation with our medical team to learn if Tesa/Ipa/MOTS-c peptide therapy is right for your body composition and metabolic optimization goals.
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Or call us directly: +1 213-325-3373
*These statements have not been evaluated by the Food and Drug Administration. This peptide combination is not FDA-approved for body composition optimization or metabolic enhancement. Use is off-label and administered under medical supervision for therapeutic purposes. Individual components have varying levels of regulatory approval and research support. Results vary by individual based on genetics, diet, training, and adherence. This blend may affect glucose metabolism, insulin sensitivity, and growth hormone levels. Contraindicated in patients with active malignancy, uncontrolled diabetes, pituitary disorders, or certain medical conditions. A consultation with our medical team and comprehensive laboratory testing are required to determine if this therapy is appropriate for you. This product is intended for use only under qualified medical supervision.
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