Product ID T7036
Cas No. 57773-63-4
Purity ≥98%
Product Unit Size Cost Quantity Stock
Description Product Info Shipping and Storage Downloads References Custom Order
Description
Triptorelin is a peptide analog of gonadotropin-releasing hormone (GnRH) that induces constant stimulation of the pituitary gland, decreasing release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Triptorelin exhibits anticancer and anxiolytic activities. Triptorelin inhibits cell proliferation in cellular models of breast cancer and ovarian cancer. This compound also increases open arm entries and social interaction time in animal models of anxiety.
Product Info
Cas No.
57773-63-4 Purity
≥98% Formula
C64H82N18O13 Formula Wt.
1311.5 Chemical Name
5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D- tryptophyl-L-leucyl-L-arginyl-L-prolylglycinamide IUPAC Name
(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[ (2S)-2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-5- (diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan- 2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(4- hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino] -3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1- oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide Synonym
Decapeptyl, [DTrp6]-LH-RH, Amide Solubility
Soluble in water. Appearance
White to off white powder
Shipping and Storage
Store Temp
-20°C Ship Temp
Ambient
References
Saleh-Abady MM, Alizadeh A, Shamsipour F, et al. The anticancer activity compared between triptorelin and a new gonadotropin releasing hormone analogue. Avicenna J Med Biotechnol. 2009 Jul;1(2):105-10. PMID: 23407883.
Umathe SN, Bhutada PS, Jain NS, et al. Effects of central administration of gonadotropin-releasing hormone agonists and antagonist on elevated plus-maze and social interaction behavior in rats. Behav Pharmacol. 2008 Jul;19(4):308-16. PMID: 18622178.