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CJC-1295 DAC Dosing Protocol: 2 mg Vial — Once-Weekly GHRH

CJC-1295 DAC 2 mg vial: 2 mg/mL, 1–2 mg once weekly (50–100 units). 6–8 day half-life. IGF-1 monitoring. Reviewed Feb 2026. Reviewed Feb 2026.

Context first

Study findings do not automatically establish clinical benefit, safety, dosing, or suitability for an individual.

CJC-1295 DAC Dosing Protocol: 2 mg Vial — Weekly Dosing Schedule & Supplies

Complete CJC-1295 DAC protocol for the 2 mg vial — the long-acting GHRH analogue with Drug Affinity Complex for once-to-twice weekly subcutaneous dosing.

Quickstart highlights

CJC-1295 DAC contains the GHRH 1-29 analogue with a Drug Affinity Complex (DAC) — a maleimidoproprionic acid lysine modification that covalently binds serum albumin in vivo, extending the half-life from ~30 minutes (No DAC) to approximately 6–8 days.

Concentration: 2 mg/mL (2 mg vial + 1 mL bacteriostatic water).

At 2 mg/mL: 1 mg = 50 units, 2 mg = 100 units (full vial).

CJC-1295 DAC half-life: approximately 6–8 days; once-weekly injection maintains GH elevation.

Teichman et al. (2006): once-weekly CJC-1295 DAC raised IGF-1 by 35–70% above baseline at 4 weeks.

One 2 mg vial provides 1 full dose (2 mg weekly) or 2 half-doses (1 mg biweekly).

Dosing table

For educational reference only. Your prescribing provider may adjust doses based on your clinical profile and response.

1-4

1000

50

Once weekly

1 mg — 50 units; one 2 mg vial provides 2 weekly doses

5-12

2000

100

2 mg — 100 units (full vial); reassess after 4 weeks

13+

Twice weekly

2 mg 2x weekly for maximum GH elevation; 1 vial per injection

Gradual approach

1-8

500

25

0.5 mg conservative start — 25 units; one 2 mg vial provides 4 doses

9-16

1 mg — 50 units; advance only if well tolerated

Your free CJC-1295 DAC tracker

Dose reminders

Injection logging

Cycle progress

Reconstitution steps

Draw 1 mL bacteriostatic water; inject slowly down the vial wall to avoid foaming.

Swirl gently until the lyophilized powder fully dissolves; do not shake.

Final concentration: 2 mg/mL (2,000 μg/mL). At 2 mg/mL: 1 mg = 50 units on a U-100 syringe.

Label with date; refrigerate at 2–8 °C. Use within 28 days.

Supplies needed

8-week plan

4 vials

8 syringes

4 mL bac water

8 alcohol swabs

12-week plan

6 vials

12 syringes

6 mL bac water

12 alcohol swabs

Protocol overview & cycle notes

Achieve sustained GH elevation through the convenient once-weekly CJC-1295 DAC injection protocol, using the 2 mg vial for single or double-dose supply without the complexity of daily GHRH injections.

Cycle length: 12 weeks on.

Off-cycle: 4–6 weeks off after every 12-week cycle; check IGF-1 levels.

Storage & handling

Injection & tracking tips

CJC-1295 DAC's 7–8 day half-life provides sustained GH elevation between once-weekly injections — unlike CJC-1295 No DAC (modified GRF 1-29) which requires 2–3 daily injections.

Inject at any time of day; DAC's sustained action negates the timing precision required for No-DAC peptides.

Do not combine CJC-1295 DAC with daily GHRP injections if IGF-1 rises above 300 ng/mL — monitor every 6 weeks.

Tracking

Logging helps you and your provider spot patterns and adjust dose or timing.

Measure IGF-1 at baseline, 6 weeks, and 12 weeks; CJC-1295 DAC raises IGF-1 significantly with once-weekly dosing.

Track morning fasting glucose monthly — sustained GH elevation can impair insulin sensitivity.

Monitor for water retention (ankle edema, weight gain) in the first 4 weeks — common with DAC-formulation GH peptides.

How this works & references

Sources

Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. Teichman SL et al. — J Clin Endocrinol Metab — 2006

Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects. Sackmann-Sala L et al. — Growth Horm IGF Res — 2009

Frequently asked questions

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This content is for informational purposes only and does not constitute medical advice. Consult a licensed healthcare provider before starting any peptide therapy. Dosing and protocols may vary by formulation and prescriber.

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