Protocol Overview
Dosing Protocol
Introductory
100 mcg
2x daily (AM + PM)
2 weeks
Standard
3x daily (AM, post-WO, PM)
12-16 weeks
Advanced
200 mcg
Saturation
1 mcg/kg
1-2 mcg/kg
3x daily
Key principle: Both peptides must be taken on an empty stomach. Fat and carbohydrates blunt GH release. Wait at least 30 minutes after injection before eating. The pre-bed dose is most important as it amplifies the natural nocturnal GH surge.
Reconstitution Guide
CJC-1295 no DAC (2mg vial)
Diluent: 2mL bacteriostatic water
Concentration: 1mg/mL (1,000mcg/mL)
100mcg dose: 10 units on insulin syringe
Vial yield: 20 doses at 100mcg
GHRP-2 (5mg vial)
Diluent: 2.5mL bacteriostatic water
Concentration: 2mg/mL (2,000mcg/mL)
100mcg dose: 5 units on insulin syringe
Vial yield: 50 doses at 100mcg
Note: Can be drawn into same syringe as CJC-1295
Administration Guide
Injection Protocol
Syringe: 29-31ga insulin syringe
Sites: Abdominal fat, thigh, deltoid
Combine: Draw both peptides into one syringe
Fasting: No food 30 min before/after injection
Best timing: AM fasted, post-workout, 30 min before bed
Storage & Handling
Pre-reconstitution: Room temp or refrigerated
Post-reconstitution: Refrigerate at 2-8°C
Stability: 28-30 days once reconstituted
Do not freeze: Freezing damages reconstituted peptides
Expected Timeline
Side Effects & Monitoring
Common Side Effects
Increased appetite/hunger (GHRP-2 ghrelin effect)
Water retention in first 1-2 weeks
Tingling/numbness in extremities (transient)
Mild head rush immediately post-injection
Vivid dreams/deeper sleep
GHRP-2 has stronger appetite stimulation than GHRP-6 but less than MK-677. This can be managed with timing.
Precautions
Monitor blood glucose (GH can reduce insulin sensitivity)
GHRP-2 raises cortisol and prolactin transiently
Avoid exceeding saturation dose (diminishing returns)
Not recommended with active cancer (GH/IGF-1 proliferative)
Cycle appropriately to maintain pituitary sensitivity
Stacking Recommendations
Compatible Compounds
Ipamorelin: Can alternate with GHRP-2 for lower cortisol/prolactin
BPC-157: Enhanced recovery and gut health
TB-500: Tissue repair synergy
AOD-9604: Additional fat loss via hGH fragment pathway
MK-677: Oral GH secretagogue for off-injection days
Popular Stacks
GH Optimization: CJC/GHRP-2 3x/day + MK-677 25mg at night
Recovery: CJC/GHRP-2 2x/day + BPC-157 + TB-500
Recomp: CJC/GHRP-2 3x/day + AOD-9604 300mcg
Blood Work Recommendations
GH / IGF-1
IGF-1, GH serum
Baseline, Week 6, Week 12
Metabolic Panel
Fasting glucose, insulin, HbA1c
Baseline, Week 8, Week 16
Hormonal
Cortisol, prolactin, thyroid (TSH, fT3, fT4)
Baseline, Week 8
Liver/Kidney
CMP, ALT, AST, creatinine
Baseline, Week 12
IGF-1 is the primary marker for GH axis optimization. Monitor fasting glucose as chronic GH elevation can reduce insulin sensitivity. Check prolactin if using GHRP-2 long-term.
Related Tools & Resources
Related Resources