Tesamorelin Dosage Calculator
Calculate Tesamorelin units per dose. Enter your vial (mg), bacteriostatic water, and dose — get the exact syringe units, draw volume, and how many doses your vial holds.
The Tesamorelin dosage calculator on this page does one job well: it turns a milligram vial, the volume of bacteriostatic water you add, and the milligram dose you want into the exact number of units to pull on a U-100 insulin syringe. Tesamorelin is a milligram-dosed peptide, so the number that trips people up is not a unit conversion but the injection volume — a single dose can fill a large part of the barrel, and this tool shows you exactly where to stop.
Below the calculator you will find the four formulas it runs, a fully worked example built on a 10 mg vial, the clinically studied 2 mg regimen presented as reference context (not advice), guidance on how much water to add, a plain-English walkthrough of reading units, and reference tables for the 5 mg, 10 mg, and 20 mg vial sizes. Everything here is written for a subcutaneous, injectable-first audience and is intended as research reference only, not medical advice.
How the Tesamorelin dosage calculator works
Reconstitution is only four small pieces of arithmetic, and the calculator runs them in the same order every time so the result is repeatable no matter which vial or dose you enter. Understanding the steps is worth a couple of minutes because it lets you sanity-check the tool instead of trusting a black box.
Step 1 — Concentration
Concentration is how many milligrams of peptide sit in each millilitre of liquid once you have added water. It is simply the vial strength divided by the water volume. A 10 mg vial reconstituted with 2 mL of bacteriostatic water holds 10 ÷ 2 = 5 mg per mL. This is the number that changes when you add more or less water; the total amount of peptide in the vial never changes.
Step 2 — Draw volume
Draw volume is the dose divided by the concentration. Using the numbers above, a 2 mg dose ÷ 5 mg/mL = 0.4 mL. That is the physical amount of liquid you pull into the barrel. Because tesamorelin doses are already in milligrams, there is no microgram conversion to trip over — the whole risk is simply reading that 0.4 mL correctly on a syringe marked in units.
Step 3 — Units on the syringe
A U-100 insulin syringe is graduated in units, where 100 units equals 1 mL. So units = draw mL × 100. Here, 0.4 mL × 100 = 40 units. That is the mark you fill to. A 2 mg tesamorelin dose is a comparatively large injection volume, which is exactly why seeing the unit mark up front matters.
Step 4 — Doses per vial
Doses per vial tells you how long a vial lasts: vial mg ÷ dose mg, rounded down. A 10 mg vial at a 2 mg dose gives 10 ÷ 2 = 5 doses. Knowing this before you start lets you plan a schedule instead of running short mid-way.
Worked example: 10 mg vial, 2 mL water, 2 mg dose
Let’s run the exact configuration this calculator loads by default, step by step, so every number lines up. Inputs: a 10 mg vial, 2 mL of bacteriostatic water, a target dose of 2 mg, drawn on a U-100 syringe.
Concentration: 10 mg ÷ 2 mL = 5 mg/mL.
Draw volume: 2 mg ÷ 5 mg/mL = 0.4 mL.
Syringe units: 0.4 mL × 100 = 40 units.
Doses per vial: 10 mg ÷ 2 mg = 5 doses.
Notice that 40 units is nearly half of a 1 mL barrel. That is normal for a milligram-scale peptide: if the injection volume feels large, adding less water lowers the unit count (a 10 mg vial with 1 mL of water puts the same 2 mg dose at just 20 units), at the cost of a more concentrated, less forgiving draw.
What is the clinically studied Tesamorelin dose?
For reference context only — not as a recommendation — the dose used in the clinical literature is worth knowing because it anchors what “a tesamorelin dose” usually means. Tesamorelin is the active ingredient in the FDA-approved product Egrifta (and its reformulations Egrifta SV / Egrifta WR), where the studied and labeled regimen is 2 mg injected subcutaneously once daily. Its single approved indication is the reduction of excess abdominal fat in adults with HIV-associated lipodystrophy — it is not approved for general body-composition, anti-aging, or growth-hormone-optimization use.
The calculator defaults to a 2 mg dose because it is the well-characterised reference figure, but the tool itself is dose-agnostic: enter any dose your protocol specifies and it recomputes instantly. For documented, compound-specific detail, see the Tesamorelin 10 mg dosage protocol and the standalone tesamorelin protocol.
How much bacteriostatic water should you add?
There is no single correct water volume; there is only a range that makes measuring easy and keeps the liquid inside the vial. Remember that water changes concentration, not potency. Adding more water spreads the same peptide across more liquid, so each dose becomes more units on the syringe. Adding less water concentrates it, so each dose becomes fewer units.
Two practical limits bracket the useful range. First, the water has to physically fit inside the vial — peptide vials typically hold around 2 to 3 mL of headroom for small vials, so very large fills are not an option. Second, you want a dose that lands on a readable, single-syringe number of units. For a 2 mg tesamorelin dose, a 10 mg vial with 1 to 2 mL of water keeps you between roughly 20 and 40 units, which is comfortably inside one U-100 barrel. Going to 3 mL pushes the same dose to 60 units, which still fits but uses more of the syringe.
Reading units on a U-100 syringe
The “U-100” on an insulin syringe means it is calibrated so that 100 units of liquid equal 1 mL. Each single unit is therefore 0.01 mL. That relationship is the whole reason the calculator multiplies draw volume by 100 — it converts the millilitres your math produced into the units printed on the barrel.
To pull the worked-example dose you would fill to the 40-unit line, which is 0.4 mL. The most common reading error is confusing units with millilitres: someone aiming for “0.4” reads the 0.4 mL point as if the barrel were marked in mL, when the number they actually want is 40 on the unit scale. Always dose by the unit marks, and let the calculator tell you which mark to stop at. If a dose works out above 100 units it will not fit in one U-100 pull — the tool flags that and you either split the dose or use less water.
Tesamorelin units by vial size (5 mg, 10 mg, 20 mg)
The table below shows the concentration and the units for a 2 mg dose across sensible water volumes for each vial size, plus how many 2 mg doses each vial holds. Use it as a quick lookup, and use the calculator above for any dose or volume not listed.
5 mg
1 mL
5.00 mg/mL
40 units
2
1.5 mL
3.33 mg/mL
60 units
10 mg
10.00 mg/mL
20 units
5
2 mL
3 mL
20 mg
10
4 mL
Two things stand out. Doses-per-vial depends only on vial strength and dose size, never on the water — a 10 mg vial holds 5 doses of 2 mg whether you add 1 mL or 3 mL. And the more concentrated setups (10 mg/mL) give the smallest, tidiest 20-unit draw, but leave less room for error, so a small measurement slip changes the delivered dose by more.
If you want to change the dose rather than the water, here is how the units shift on the default 10 mg + 2 mL (5 mg/mL) setup.
1 mg
0.20 mL
1.5 mg
0.30 mL
30 units
6
2 mg
0.40 mL
2.5 mg
0.50 mL
50 units
4
Mistakes the Tesamorelin calculator catches
A calculator is most valuable when it stops an error before it happens. These are the ones that come up most often with a milligram-dosed peptide.
Drawing millilitres as if they were units. Reading 0.4 on the barrel instead of stopping at the 40-unit mark. The tool reports the answer in units precisely, so there is nothing to reinterpret.
Over-diluting into an impossible draw. Adding so much water that a single dose exceeds one syringe. The calculator warns when the draw passes 100 units and when the water volume is too large to fit a normal vial.
Assuming water changes strength. Believing more water means a weaker dose. It does not change the milligrams you inject once you re-measure the units — it only changes how many units that same dose occupies.
Not planning the vial. Forgetting to check doses-per-vial before starting, then running short mid-schedule. Seeing the doses count up front lets you plan how long a vial lasts.
What Tesamorelin is studied for
Tesamorelin is a synthetic analogue of growth-hormone-releasing hormone (GHRH) — a stabilised 44-amino-acid peptide that stimulates the pituitary to release the body’s own growth hormone, which in turn raises IGF-1. Because it works one step upstream of growth hormone itself, it is described as a GHRH analogue or secretagogue rather than growth hormone. In the clinical literature it was studied for, and is FDA-approved for, reducing excess visceral (abdominal) fat in people with HIV-associated lipodystrophy at 2 mg subcutaneously daily.
Outside that single approved indication, tesamorelin is handled as a research compound, and the research-grade material sold for laboratory use is not the approved Egrifta product. This page covers only the arithmetic of preparing a known milligram vial to a chosen dose, not a dosing protocol or a recommendation to use it. For documented, compound-specific ranges and references, see the linked protocol library rather than relying on the calculator alone. To understand how it differs from adjacent GHRH and GHRP peptides, compare Tesamorelin vs Sermorelin and Tesamorelin vs CJC-1295.
Run your numbers
Enter your own vial size, water volume, and target dose into the Tesamorelin dosage calculator above and it will return concentration, draw volume, units, and doses per vial instantly. When you want the reasoning behind a specific configuration in plain language, ask the OpenPeptide assistant. For documented specifics, see the Tesamorelin 5 mg protocol and 10 mg protocol; for a full walkthrough of mixing technique, storage, and syringe handling, read the peptide reconstitution guide; and for any term you are unsure about, check the peptide glossary.
Frequently asked questions
It converts a vial's milligram strength, the millilitres of bacteriostatic water you add, and your target milligram dose into the exact units to draw on a U-100 insulin syringe. It also reports the vial's concentration and how many doses the vial contains.
That gives a concentration of 5 mg/mL, a draw of 0.4 mL, which is 40 units on a U-100 syringe. The same 10 mg vial holds 5 doses of 2 mg.
Concentration equals vial milligrams divided by millilitres of bacteriostatic water. A 10 mg vial reconstituted with 2 mL of water is 10 divided by 2, or 5 mg per mL.
Between 1 and 3 mL works well. One to 2 mL keeps a 2 mg dose between about 20 and 40 units, comfortably inside a single U-100 barrel. The water must physically fit the vial, and it changes concentration only, not the total peptide.
For reference only, not as advice: tesamorelin is the active ingredient in the FDA-approved product Egrifta, studied at 2 mg injected subcutaneously once daily, solely for reducing excess abdominal fat in HIV-associated lipodystrophy. Research-grade material is not the approved product and is not for human therapeutic use.
No. Water changes concentration, not the milligrams of peptide in the vial. More water simply means each dose occupies more units on the syringe; once you re-measure the units, the actual dose injected is unchanged.
U-100 means the syringe is calibrated so that 100 units equal 1 mL, making each unit 0.01 mL. That is why the calculator multiplies the draw volume in millilitres by 100 to give units.
Divide the vial strength by the dose, rounded down. At 2 mg, a 10 mg vial holds 10 divided by 2, which is 5 doses. A 20 mg vial holds 10 doses at the same size.
Because tesamorelin is dosed in whole milligrams rather than micrograms, a single dose is many times more liquid. A 2 mg dose at 5 mg/mL is 0.4 mL, or 40 units, close to half a U-100 barrel, whereas a microgram-dosed peptide might need only a few units.
Yes. Enter any vial size, water volume, and dose, and it recomputes concentration, draw volume, units, and doses per vial. For documented compound-specific ranges, check the linked single-peptide dosage protocols.
Tesamorelin itself is FDA-approved as Egrifta for one narrow indication, abdominal fat in HIV-associated lipodystrophy, at 2 mg daily. The research-grade tesamorelin sold for laboratory use is not that approved product and is labeled for research use only, not human therapeutic use.
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