Mechanism of Action
GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic hexapeptide that stimulates growth hormone release by activating the ghrelin/growth hormone secretagogue receptor (GHS-R1a). It is one of the most potent GHRP variants, producing strong GH release along with increases in cortisol, prolactin, and appetite stimulation through ghrelin receptor activation.
Clinical Applications
Growth hormone optimization Appetite stimulation Muscle growth Anti-aging Recovery enhancement Cachexia and wasting conditions
Dosing Protocols
Typical dose: 100-300mcg subcutaneous, 2-3 times daily. Administer on empty stomach. Often combined with a GHRH analog (CJC-1295) for synergistic GH release.
Safety & Side Effects
May increase cortisol and prolactin levels (more than ipamorelin). Strong appetite stimulation. Water retention possible. Monitor cortisol and prolactin with chronic use.
Clinical Information
Category: Growth Hormone Type: Peptide Profile Audience: Healthcare Providers & Clinicians Evidence Level: Clinical research and peer-reviewed studies Source: Peptide Education Hub — The Most Comprehensive Evidence-Based Peptide Resource
Related Peptides
GHRP-6 Ipamorelin Hexarelin CJC-1295
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