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Somapacitan (Sogroya): CADTH Reimbursement Review: Therapeutic area: Growth hormone deficiency (GHD) [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2024 Jan.
Somapacitan (Sogroya): CADTH Reimbursement Review: Therapeutic area: Growth hormone deficiency (GHD) [Internet].
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Table 8CADTH Cost Comparison Table for Human Growth Hormones to Treat Growth Hormone Deficiency
Treatment Strength / concentration Form Price ($) Recommended dosage Daily cost ($) Annual cost ($) Somapacitan (Sogroya) 5 mg / 1.5 mL
10 mg / 1.5 mL
15 mg / 1.5 mL Prefilled pen 297.2000 a
594.4000 a
891.6000 a 0.16 mg/kg weekly 42.34 15,454 Somatrogon (Ngenla)b 24 mg / 1.2 mL Prefilled pen 345.8400 0.66 mg/kg weekly 42.64 15,563 60 mg / 1.2 mL 864.6000 Daily growth hormone treatment Somatropin (Genotropin) 5.3 mg
12 mg Prefilled pen 154.5840
349.9880 0.16 to 0.24 mg/kg/week, in 6 to 7 doses 20.75 to 31.64 7,575 to 11,550 0.6 mg
0.8 mg
1.0 mg
1.2 mg
1.4 mg
1.6 mg
1.8 mg
2.0 mg Single-use prefilled syringe 17.5000
23.3329
29.1657
35.0000
40.8314
46.6657
52.4986
58.3314 20.76 to 31.21 7,578 to 11,392 Somatropin (Humatrope) 6 mg / 3.15 mL
12 mg / 3.15 mL
24 mg / 3.15 mL Cartridge 315.2500
630.5000
1,261.0100 0.18 to 0.30 mg/kg/week in 3 to 7 doses 42.32 to 72.55 15,447 to 26,481 Somatropin
(Norditropin) 5 mg / 1.5 mL
10 mg / 1.5 mL
15 mg / 1.5 mL Prefilled pen 194.7000
389.4000
584.1000 Up to 0.3 mg/kg/week, divided in daily doses 51.74 18,886 Somatropin
(Nutropin AQ) 5 mg / 2 mL
10 mg / 2 mL
20 mg / 2mL Cartridge 203.7100
407.4200
814.8400 Up to 0.3 mg/kg/week, divided in daily doses 54.14 19,760 Somatropin
(Omnitrope) 5 mg
10 mg Vial 155.8000
311.6000 0.16 to 0.24 mg/kg/week 22.2 to 33.29 8,102 to 12,152 15 mg / 1.5 mL Cartridge 467.4000c 23.05 to 33.29 8,413 to 12,152 Somatropin (Saizen) 5 mg Vial 224.0500 0.20 to 0.27 mg/kg/week in 3 to 7 doses 39.9 to 54.02 14,563 to 19,716 6 mg (5.83 mg/mL)
12 mg (8 mg/mL)
20 mg (8 mg/mL) Cartridge 268.8300
537.6600
896.1000 39.77 to 54.50 14,517 to 19,893
Note: All prices are from the Ontario Exceptional Access Program16 (accessed July 2023), unless otherwise indicated, and do not include dispensing fees. Weight-based doses use a weight of 31.08 kg per the sponsor’s average patient weight estimate in the budget impact analysis.22 Annual costs are based on rounding the number of units required in a calendar year to the nearest integer. Daily costs are based on annual costs divided by 365. No other wastage costs have been considered. a
Sponsor’s submitted price. b
Somatrogon received a pricing condition from CADTH Canadian Drug Expert Committee (CDEC) in March 2022, for the long-term treatment of pediatric patients who have growth failure due to an inadequate secretion of endogenous growth hormone (growth hormone deficiency) in that it should only be reimbursed if it does not cost more than the least costly somatropin.20 c
Saskatchewan Formulary list price23 (accessed in July 2023).
From: Pharmacoeconomic Review
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