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Testosterone use and male infertility patient education fact

Revised 2021 Testosterone (also referred to as “T”) is a hormone produced in men by the testicles. It is involved in muscle and bone development, hair growth, and development of the sex organs such as the penis and prostate. It also contributes to a man’s sense of overall well-being and sexual function. Testosterone is required for sperm production as well. How do you test for low testosterone and what problems does it cause? Low testosterone is also called hypogonadism. It can lead to problems with erections, low sex drive, mood changes and problems with sperm health and sperm counts. Testosterone can be measured by a simple blood test and are usually measured in the morning, since that is when levels are highest in men. Can low testosterone be treated? Men with low testosterone can be treated! Testosterone replacement comes in many forms, including shots, gels, patches, or implantable pellets. However, it is important to know that testosterone treatment usually leads to either low sp

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Study findings do not automatically establish clinical benefit, safety, dosing, or suitability for an individual.

Revised 2021

Testosterone (also referred to as “T”) is a hormone produced in men by the testicles. It is involved in muscle and bone development, hair growth, and development of the sex organs such as the penis and prostate. It also contributes to a man’s sense of overall well-being and sexual function. Testosterone is required for sperm production as well.

How do you test for low testosterone and what problems does it cause?

Low testosterone is also called hypogonadism. It can lead to problems with erections, low sex drive, mood changes and problems with sperm health and sperm counts. Testosterone can be measured by a simple blood test and are usually measured in the morning, since that is when levels are highest in men.

Can low testosterone be treated?

Men with low testosterone can be treated! Testosterone replacement comes in many forms, including shots, gels, patches, or implantable pellets. However, it is important to know that testosterone treatment usually leads to either low sperm counts, or no sperm seen whatsoever in the semen.

Once the testosterone is stopped, the sperm should return to the semen within about 3 months, and no permanent damage is seen.

Can low testosterone lead to infertility?

Low testosterone does not directly cause infertility. Sperm production is stimulated by hormones other than testosterone. Testosterone is required for sperm production, but the level in the testes where sperm is produced is many times higher than in the blood. Even men with low or borderline T levels may have sufficient T levels for sperm production, but it may contribute to lower counts or less healthy sperm.

If a man is taking testosterone and wants to have children, how can low testosterone be treated to help with fertility?

There are some medications that can lower estrogen levels in your body. All men have estrogen in them but lowering it may help with sperm production. These meds include clomiphene citrate, letrozole or anastrozole and are pills. There are also injectable drugs that act like the hormones sent down from glands in your brain that will increase sperm production. Fertility specialists for males will prescribe these drugs, because sometimes they can act to lower sperm counts if they are used incorrectly.

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SART Fertility Experts - The Strength to Speak: Men, Infertility, and the Weight of Silence

Male infertility is common, but the emotional toll often remains hidden behind silence, stigma, and expectations about masculinity. Listen to the Episode

Half of Infertility Cases Involve Men. Why Does Care Still Treat It as a Women’s Issue?

Since 1989, National Infertility Awareness Week (NIAW) has marked a critical moment each April to elevate public understanding of infertility and push for better care. View the Press Release

SART Fertility Experts - Azoospermia

Learn about azoospermia, its causes, diagnosis, and treatment options from top fertility experts. Early testing is key to effective infertility care. Listen to the Episode

SART Fertility Experts - Wellness and Fertility: Diet, Sleep and Exercise

Drs. Timothy Hickman and Rashmi Kudesia discuss the links between lifestyle and fertility. Listen to the Episode

Male Fertility Journey

About 20% of infertility cases are due to a male factor alone. Another 30% involves both male and female factors.

View the Patient Journey

SART Fertility Experts - Urology and Male Reproductive Health

Male infertility is less often discussed than female infertility. Dr. Ajay Nangia discusses when a man should seek help with conceiving.

Listen to the Episode

Stress and infertility

It is not clear how exactly stress impacts fertility. Read the Fact Sheet

Optimizing Natural Fertility

Before attempting pregnancy, a woman should make sure she is healthy enough for pregnancy by adopting a healthier lifestyle and taking prenatal vitamins. If she has a medical or genetic condition or risk of one, she should seek advice from a medical professional before conceiving (becoming pregnant) View the fact sheet

Optimizing Male Fertility

About 20% of infertility cases are due to a male factor alone. Another 30% involves both male and female factors. View the fact sheet

Cancer and its impact on sperm, cryopreservation, and fertility

This can be confusing since the terms are often used interchangeably in the media and casual conversation. View the fact sheet

Male Fertility Evaluation: What do I need to know?

Infertility is the inability to achieve pregnancy after one year of unprotected sex. View the fact sheet

Sperm morphology (shape): Does it affect fertility?

The most common test of a man’s fertility is a semen analysis. View the fact sheet

Fertility Options for Men with Spinal Cord Injury

There are several reasons a man with a spinal cord injury (SCI) might have infertility. View the fact sheet

Varicocele

A varicocele is a variation of normal anatomy in which veins in the scrotum (the sac that holds the testicles) become enlarged and sometimes even visible. View the fact sheet

Weight and fertility

One of the easiest ways to determine if you are underweight or overweight is to calculate your body mass index (BMI). View the fact sheet

ERKEK FERTİLİTESİNİN OPTİMİZASYONU

Normal bir heteroseksüel çiftin bir yıl içinde hamile kalma şansı yaklaşık %85’tir. View the fact sheet

ERKEK KANSERİ DONDURARAK SAKLAMA VE DOĞURGANLIK

Terimler genellikle medyada ve gündelik konuşmalarda birbirinin yerine kullanıldığı için bu kafa karıştırıcı olmakla birlikte bu iki terim birbirinden oldukça farklıdır. View the fact sheet

ERKEKTE KISIRLIĞIN DEĞERLENDİRİLMESİ

Kısırlık, bir yıl boyunca korunmasız cinsel ilişkiye rağmen gebelik elde edilememesi olarak tanımlanır. View the fact sheet

İnfertilite İçin Tanısal Testler

Gebelik elde edememiş çiftlere, korunmasız şekilde 12 ay boyunca denemelerine rağmen gebe kalamamışlarsa fertilite testleri önerilmektedir. View the fact sheet

Kilo ve Doğurganlık

Gebelik için ideal kiloda olup olmadığınızı anlamanın en kolay yollarından biri, vücut kitle indeksinizi (VKİ) hesaplamaktır. View the fact sheet

Varikosel

Varikosel, skrotumda (testisleri tutan torba) bulunan damarların genişlemesidir. View the fact sheet

SART Fertility Experts - Male Factor

Infertility is not just a female problem. Dan candidly shares his journey with both diagnosis and treatment of male infertility with Dr. Paul Lin.

Listen to the Episode

Intracytoplasmic sperm injection (ICSI)

A procedure called intracytoplasmic sperm injection (ICSI) can be done along with in vitro fertilization (IVF) if a sperm cannot penetrate the outer layer of an egg. Read the Fact Sheet

SART Fertility Experts - IVF: Cycles of Hope and Heartbreak

Does stress cause infertility or is it the other way round? Listen to the Episode

Fertility Options After Vasectomy

Vasectomy is currently one of the most common methods of sterilization in the United States. After your vasectomy, if you change your mind about having children, there are two procedures that can help you have a child with your partner. View the Fact Sheet

Testosterone use and male infertility

Testosterone (also referred to as “T”) is a hormone produced in men by the testes (testicles). View the fact sheet

SART Fertility Experts - Male Fertility

Did you know that up to 40% of infertile couples suffer from male factor infertility? Listen to the Episode

Infertility: an Overview (booklet)

Infertility is typically defined as the inability to achieve pregnancy after one year of unprotected intercourse. View the booklet

Male Fertility and Infertility - a patient education video

Male Factor Infertility is responsible for about 30% of infertility cases and can contribute infertility to an additional 20% of cases. Watch Video

Infertility

Infertility is the result of a disease (an interruption, cessation, or disorder of body functions, systems, or organs) of the male or female reproductive tract which prevents the conception of a child or the ability to carry a pregnancy to delivery. Watch Video

Basic Infertility Evaluation

Dr. Roger Lobo of the American Society for Reproductive Medicine discusses the various methods to evaluate infertility. Watch Video

Infertility Treatments

Dr. Roger Lobo of the American Society for Reproductive Medicine discusses the various treatments for infertility. Watch Video

Understanding Fertility

In this video series, Dr. Roger Lobo explains the basics of infertility, including causes, treatments and coping methods. Watch Video

Surviving the Roller Coaster Emotions of Infertility Treatment

The experience of infertility is a rollercoaster of hope and disappointment. Treatment presents an opportunity for hope as well as a new set of challenges. Watch Video

Causes of Male Infertility

Dr. Roger Lobo, of the American Society for Reproductive Medicine explains the causes of male infertility. Watch Video

FAQ About Infertility

Infertility is not an inconvenience; it's a disease of the reproductive system. Learn the facts

Male Fertility Infographics

ASRM has prepared infographics to illustrate the subject of Male Fertility better. View the infographics

Half of Infertility Cases Involve Men. Why Does Care Still Treat It as a Women’s Issue?

Since 1989, National Infertility Awareness Week (NIAW) has marked a critical moment each April to elevate public understanding of infertility and push for better care. View the Press Release

National Infertility Awareness Week Highlights Record IVF Births, Growing Demand for Fertility Care

IVF births surpass 100,000 in one year, highlighting demand for fertility care as ASRM urges awareness, reduced stigma, and expanded access nationwide. View the Press Release

SART Fertility Experts: Complimentary and Integrative Medicine in Reproductive Care and Infertility Treatment

Explore how acupuncture and naturopathic care support IVF, endometriosis, and fertility in this ASRM expert talk on integrative reproductive medicine. Listen to the Episode

Follow the Science: An Evidence-Based, Science-Driven Response to Infertility

A science-based infertility evaluation and treatment guide, grounded in clinical best practices, counters ideologically driven alternatives like RRM. View the advocacy resource

National Infertility Awareness Week

April 18-24, 2027, is National Infertility Awareness Week (NIAW)!

View the NIAW Toolkit

SART Fertility Experts - Military Families and Fertility

Active-duty individuals in the military sometimes face unique circumstances when seeking fertility care. Learn more with a former military fertility physician. Listen to the Episode

SART Fertility Experts - Q&A on Infertility

Infertility can create many questions for a patient. Listen to common questions and answers about infertility, egg freezing, and genetic testing. Listen to the Episode

SART Fertility Experts - Environmental Impacts on Fertility

In this episode, the fertility experts discuss the impact of the environment, including air, climate, and chemical exposures on infertility. Listen to the Episode

SART Fertility Experts - Recurrent Pregnancy Loss and Implantation Failure

"I can get pregnant, but I can't stay pregnant," is echoed by patients with recurrent pregnancy loss. Listen to the Episode

SART Fertility Experts - Wellness and Fertility: Diet, Sleep and Exercise

Drs. Timothy Hickman and Rashmi Kudesia discuss the links between lifestyle and fertility. Listen to the Episode

SART Fertility Experts - Navigating IVF as a Couple

Mary Casey Jacob, PhD is interviewed by Dr. Daniel Grow, and together they explore the emotional and practical support that couples need. Listen to the Episode

Male Fertility Journey

About 20% of infertility cases are due to a male factor alone. Another 30% involves both male and female factors.

View the Patient Journey

Female Fertility Journey

If you've been trying to get pregnant for more than a year, you may have infertility. Infertility is a disease of the reproductive system that impairs one of the body's most basic functions: the conception of children.

View the Patient Journey

Hyperprolactinemia (High Prolactin Levels)

Prolactin is a hormone produced by your pituitary gland which sits at the bottom of the brain. Read the fact sheet

Stress and infertility

It is not clear how exactly stress impacts fertility. Read the Fact Sheet

Optimizing Natural Fertility

Before attempting pregnancy, a woman should make sure she is healthy enough for pregnancy by adopting a healthier lifestyle and taking prenatal vitamins. If she has a medical or genetic condition or risk of one, she should seek advice from a medical professional before conceiving (becoming pregnant) View the fact sheet

Optimizing Male Fertility

About 20% of infertility cases are due to a male factor alone. Another 30% involves both male and female factors. View the fact sheet

Defining Infertility

Infertility is “the inability to conceive after 12 months of unprotected intercourse.” View the Fact Sheet

Fertility Rights and Responsibilities

Can a fertility program or clinic deny treatment to patient(s) if there is concern about the ability to care for the child(ren)? Yes. Fertility programs can withhold services if there are signs that patients will not be able to care for child(ren). View this Fact Sheet

What is In Vitro Maturation (IVM)?

In vitro maturation (IVM) is when a woman’s eggs are collected and matured outside the body. This is done as part of an in vitro fertilization (IVF) procedure. View the fact sheet

Infertility Counseling and Support: When and Where to Find It

Infertility is a medical condition that touches all aspects of your life. View the fact sheet

Male Fertility Evaluation: What do I need to know?

Infertility is the inability to achieve pregnancy after one year of unprotected sex. View the fact sheet

Smoking and infertility

Most people understand that smoking increases the risk for heart, vascular, and lung disease. View the fact sheet

What are fibroids?

Uterine fibroids (also called myomas or leiomyomas) are benign (noncancerous) tumors of muscle tissue found in the uterus. View the fact sheet

İn Vitro Maturasyon (IVM)

İn vitro maturasyon (IVM), yumurtaların vücut dışında toplanıp olgunlaştırılması işlemidi. View the fact sheet

İnfertilite İçin Tanısal Testler

Gebelik elde edememiş çiftlere, korunmasız şekilde 12 ay boyunca denemelerine rağmen gebe kalamamışlarsa fertilite testleri önerilmektedir. View the fact sheet

KISIRLIĞIN (İNFERTİLİTENİN) TANIMLANMASI

Kısırlık “12 aylık korunmasız ilişkiye karşın gebe kalamamadır. View the fact sheet

Sigara ve Kısırlık

Çoğu insan, sigara içmenin kalp, damar ve akciğer hastalıkları riskini artırdığını bilir. View the fact sheet

SART Fertility Experts - Endometriosis

Endometriosis is a condition that can affect many facets of a person’s life, from pelvic pain to struggles with infertility. Listen to the Episode

SART Fertility Experts - Recurrent Pregnancy Loss

Candace discusses her experience with infertility, IVF, multiple pregnancy losses and ultimately a successful delivery with Dr. Julia Woodward. Listen to the Episode

SART Fertility Experts - Financial Aspects of Infertility Treatment

“I know what treatment I want and need to do, but how can I afford it?” This is a common question infertility patients often ask themselves. Listen to the Episode

SART Fertility Experts - Infertility Advocacy and Government Affairs

In today's episode, Dr. Mark Trolice interviews Sean Tipton about the fact that many infertility patients do not have insurance coverage for treatment. Listen to the Episode

SART Fertility Experts - Your Infertility Nurse: Partner in Your Care

Infertility nurse practitioner and health coach Monica Moore explains the essential role of the infertility nurse in the IVF process. Listen to the Episode

Intracytoplasmic sperm injection (ICSI)

A procedure called intracytoplasmic sperm injection (ICSI) can be done along with in vitro fertilization (IVF) if a sperm cannot penetrate the outer layer of an egg. Read the Fact Sheet

SART Fertility Experts - IVF: Cycles of Hope and Heartbreak

Does stress cause infertility or is it the other way round? Listen to the Episode

SART Fertility Experts - RESOLVE and Infertility

Due to the unique stress of infertility, patients often look for resources and support in addition to those provided by their medical provider. Listen to the Episode

What is Recurrent Pregnancy Loss (RPL)?

This is a condition when a woman has 2 or more clinical pregnancy losses (miscarriages) before the pregnancies reach 20 weeks. View the fact sheet

What is Premature Ovarian Insufficiency (Previously Called Premature Ovarian Failure)?

When a woman’s ovaries stop working before age 40, she is said to have premature ovarian insufficiency (POI). View the fact sheet

Saline infusion sonohysterogram (SHG)

Saline infusion sonohysterography (SIS or SHG) is aprocedure to evaluate the uterus and the shape of the uterine cavity. View the fact sheet

SART Fertility Experts - Safe Surfing: The Pros and Perils of Social Media

Dr. Kenan Omurtag, MD joins host Dr. Mark Trolice to discuss the use of social media in the field of infertility. Listen to the Episode

SART Fertility Experts - What is an REI?

These experts in infertility lead IVF programs, perform reproductive surgery, and perform research to enhance the field of reproductive medicine. Listen to the Episode

SART Fertility Experts Teaser

An educational project of SART, this series is designed to provide up-to-date information about various topics related to fertility testing and treatment.

Listen to the Episode

Stress and Infertility

Medical procedures, cost, outcome uncertainty, and unwanted or unhelpful advice from friends and family are stressors associated with infertility treatment. Watch Video

Infertility: an Overview (booklet)

Infertility is typically defined as the inability to achieve pregnancy after one year of unprotected intercourse. View the booklet

Male Fertility and Infertility - a patient education video

Male Factor Infertility is responsible for about 30% of infertility cases and can contribute infertility to an additional 20% of cases. Watch Video

Infertility

Infertility is the result of a disease (an interruption, cessation, or disorder of body functions, systems, or organs) of the male or female reproductive tract which prevents the conception of a child or the ability to carry a pregnancy to delivery. Watch Video

Basic Infertility Evaluation

Dr. Roger Lobo of the American Society for Reproductive Medicine discusses the various methods to evaluate infertility. Watch Video

Fibroid Tumors

An educational video that answers patient questions about the causes, symptoms, diagnosis and management of uterine fibroids. Watch Video

Infertility Treatments

Dr. Roger Lobo of the American Society for Reproductive Medicine discusses the various treatments for infertility. Watch Video

Understanding Fertility

In this video series, Dr. Roger Lobo explains the basics of infertility, including causes, treatments and coping methods. Watch Video

Surviving the Roller Coaster Emotions of Infertility Treatment

The experience of infertility is a rollercoaster of hope and disappointment. Treatment presents an opportunity for hope as well as a new set of challenges. Watch Video

Sexual dysfunction and infertility

Sexual dysfunction is a problem in a person’s sexual desire, arousal, or orgasm. View the fact sheet

Coping With Infertility

Dr. Roger Lobo of the American Society for Reproductive Medicine discusses various methods of coping with infertility. Watch Video

Endometriosis

Endometriosis is a condition in which endometrial tissue, which normally lines the uterus, develops outside of the uterine cavity in abnormal locations. Watch Video

Causes of Female Infertility

Dr. Roger Lobo, of the American Society for Reproductive Medicine explains the causes of female infertility. Watch Video

Age and Fertility (booklet)

Generally, reproductive potential decreases as women get older, and fertility can be expected to end 5 to 10 years before menopause. View the Booklet

Causes of Male Infertility

Dr. Roger Lobo, of the American Society for Reproductive Medicine explains the causes of male infertility. Watch Video

FAQ About Infertility

Infertility is not an inconvenience; it's a disease of the reproductive system. Learn the facts

FAQ About the Psychological Component of Infertility

Infertility often creates one of the most distressing life crises that a couple has ever experienced together. Learn the facts

Mary Dolan's Story

I was diagnosed with diminished ovarian reserve/premature ovarian failure at 28 years old.

Read the story

Infertility Infographics

ASRM has prepared infographics to illustrate the subject of Infertility better. View the infographics

Fact Sheets/Booklets

View more fact sheets and booklets written by the ASRM Patient Education Committee.

Osteoporosis

Osteoporosis and osteopenia are conditions of having low bone mass (density).

The American Society for Reproductive Medicine (ASRM) is committed to providing patients with the highest quality information about reproductive care.

Advocacy Resources

ASRM has prepared resources to help you explain and advocate for reproductive rights and the continuation of in vitro fertilization and other fertility treatments.

View the Resouces

Fact Sheets and Infographics

ASRM produces a series of fact sheets and booklets on various topics related to infertility, reproductive health, and family planning. The fact sheets and booklets are available in English, Spanish, and Chinese.

Read our Fact Sheets

SART Fertility Experts Podcast

An educational project of ASRM's affiliated society, the Society for Assisted Reproductive Technology (SART), this series is designed to provide up to date information about a variety of topics related to fertility testing and treatment such as IVF.

Listen to an Episode

Terms and Definitions

Find explanations for the meaning behind the doctor-speak you hear when trying to research reproductive medicine topics. ASRM has defined the most popular terms in easy to understand language.

Know your Medical Terms

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