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UK HPLC Tested - UKAS & ISO 9001 - >99% Purity
-20°C Cold-Chain Storage
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Certificate of Analysis (COA): Available here
PEG-MGF (Pegylated Mechano Growth Factor) is a synthetic, pegylated variant of Mechano Growth Factor, itself an isoform of Insulin-like Growth Factor-1 (IGF-1). The pegylation process is designed to extend the peptide’s stability and half-life in research environments, making it an attractive subject for laboratory investigation. PEG-MGF has gained significant attention in preclinical studies focused on muscle growth, repair, and regeneration.
Area of Interest
Research into PEG-MGF has highlighted several promising areas:
Muscle Repair: Explored for its role in stimulating satellite cell activation and muscle fiber regeneration following injury. Hypertrophy Studies: Studied in preclinical models for its influence on muscle mass and protein synthesis. Longevity of Action: The pegylation modification allows for extended half-life compared to regular MGF, making it of particular interest in long-term dosing models. Cellular Growth Pathways: Investigated as part of IGF-1 related signaling pathways involved in tissue repair and growth.
Together, these research areas underscore PEG-MGF as a peptide of high interest, particularly in the field of muscle biology and recovery research.
Technical Information
Chemical Name: Pegylated Mechano Growth Factor Synonyms: PEG-MGF, Pegylated IGF-1 Ec isoform Molecular Formula: Variable due to pegylation (core MGF sequence plus PEG chain) Molecular Weight: ~2867 g/mol (unmodified MGF, higher with PEG modification) Sequence (Amino Acid): Derived from IGF-1 Ec splice variant; sequence varies slightly depending on manufacturer CAS Number: Not consistently assigned (research peptide) Peptide Classification: Synthetic peptide, pegylated for stability
Storage Guidelines
Lyophilized peptide is stable at room temperature for short periods. For long-term storage, keep at −20 °C or below. Once reconstituted, store at 2–8 °C. Effective use period may vary depending on the solution used.
Solubility
PEG-MGF is soluble in sterile water or other aqueous buffers depending on formulation and purity.
References
Goldspink, G. (2005). “Gene expression in muscle in response to exercise.” Journal of Muscle Research and Cell Motility, 26(2-3), 121–126. https://doi.org/10.1007/s10974-005-9010-0 Yang, S. Y., Goldspink, G. (2002). “Different roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiation.” FEBS Letters, 522(1-3), 156–160. https://doi.org/10.1016/S0014-5793(02)02918-6
Certificate of Analysis (COA): Available here
PEG-MGF
Feature
Tide Labs
Typical suppliers
Purity Testing
Independent HPLC at a UKAS & ISO 9001 accredited UK lab
Self-reported or overseas lab with no accreditation
Certificate of Analysis
Full COA's - UK Tested, 99%+ Purity
Generic or unavailable — often only on request
Storage Conditions
-20°C cold-chain from receipt to dispatch
Room temperature or uncontrolled warehouse
Shipping
Temperature-shielded Mylar + same-day dispatch before 4pm
Standard packaging, 2-5 day processing
Vial Quality
Type 1 pharmaceutical-grade borosilicate glass
Type 2/3 soda-lime glass — risk of heavy metal leaching
Supply Chain
Fully documented UK-based chain of custody
Opaque — often rebadged from unknown overseas sources
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