Buy CJC-1295 Without DAC 2mg Research Peptide Online
CJC-1295 Without DAC Peptide Identification
CJC-1295 Without DAC (Modified GRF 1-29) is a 29-amino-acid synthetic growth hormone-releasing factor analog engineered with enhanced DPP-IV peptidase resistance through targeted amino acid substitutions at positions 2, 8, 15, and 27. This unmodified variant lacks the albumin-binding conjugation present in DAC variants, resulting in shorter circulation duration suitable for acute secretion studies in preclinical models. Supplied as lyophilized powder in 2mg vials for pulsatile GH research.
CJC-1295 Without DAC Mechanism of Action
In cell culture and animal research models, unmodified CJC-1295 activates GHRH receptor signaling pathways with rapid onset and clearance kinetics compared to its DAC-conjugated counterpart. The peptide stimulates growth hormone-releasing hormone receptor-mediated cAMP production in somatotroph cell lines, enabling investigation of pulsatile GH axis signaling patterns distinct from extended-duration DAC variants. DPP-IV resistance modifications maintain peptide integrity while permitting natural metabolic clearance through endogenous pathways.
CJC-1295 Without DAC Published Research Summary
Raun et al. (2000, Journal of Peptide Research) characterized GRF analog receptor binding affinities and DPP-IV resistance mechanisms in preclinical models. Bowers et al. (2003) documented acute versus extended secretion patterns comparing DAC and non-DAC GHRH analogs in controlled animal systems. Published literature demonstrates CJC-1295 without DAC utility in studying acute GH secretion responses distinct from chronic signaling paradigms in somatotroph cell preparations.
CJC-1295 Without DAC 2mg Product Specifications & Handling
Form: Lyophilized powder, white; Quantity: 2mg per vial; Storage: -20°C, desiccated, sealed; Reconstitution: Sterile saline or bacteriostatic water; Stability: 24 months from manufacture; Purity: >99% by analytical HPLC; Molecular weight: approximately 3.4 kDa (without DAC moiety).
CJC-1295 Without DAC Research Use Only Disclaimer
Research use only. Not for human consumption, clinical use, medical application, disease treatment, or therapeutic claims. All described mechanisms derive from preclinical research in controlled laboratory settings. Institutional review and regulatory approval required for all research applications.