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Ipamorelin is a selective growth-hormone secretagogue that binds to the growth-hormone secretagogue receptor type 1a (GHS-R1a) without significant activity at ghrelin O-acyltransferase or other pituitary hormone receptors. In in vitro and preclinical rodent models, it’s employed to dissect growth-hormone axis dynamics and downstream anabolic, lipolytic, and osteoanabolic pathways.
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Quantity Discount Price 1 0% $49.00 2 - 5 5% $46.55 6 - 10 10% $44.10 11 - 15 15% $41.65
Amino Acid Sequence
Aib–His–D-2Nal–D-3Phe–Lys–NH2
Molecular Formula
C36H49N9O5
Molecular Weight
711.82 g/mol
PubChem CID
16041794
CAS Number
170851-70-4
Vial Size
3ml
Contents
Lyophilized powder, white/off-white color
GHS-R1a Agonism & GH Secretion
Ipamorelin selectively activates GHS-R1a on somatotrophs, coupling via Gαq/11 to PLCβ → IP3/DAG signaling, triggering Ca2+-dependent exocytosis of growth hormone—yielding pulsatile release without concomitant ACTH or cortisol secretion.
Anabolic & Lipolytic Signaling
Elevated GH induces hepatic IGF-1 production, which engages the IGF-1R/PI3K/Akt pathway in muscle and adipose tissue, promoting protein synthesis and adipocyte lipolysis.
Osteoanabolic Effects
GH/IGF-1 axis activation upregulates Runx2 and osterix in osteoblasts via JAK2/STAT5 signaling, enhancing bone matrix deposition and mineralization.
Storage:
Store the lyophilized vial in a cool, dry area protected from direct sunlight.
Certificate of Analysis
99%+ Purity Guaranteed
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Always 3rd party tested
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FAQs Why Honest Peptide?
Rigorous Testing, No Exceptions: Every batch is 3rd-party tested for purity, weight, and toxins—so you can shop with total confidence. Priced Right: As a family business, we keep costs low and pass the savings directly to you. Here for You: Fast shipping and real human support, every single time. Do you test your products and provide COAs?
Yes! Every product goes through multiple 3rd-party tests to verify purity, accurate weight, and that it’s toxin-free. Each test result is documented in a Certificate of Analysis (COA), which you can download directly from each product page or from our centralized COA library. What if I have more questions?
We’re here to guide and support. Please reach out to [email protected] and we’ll respond within 1 business day. What is your shipping policy?
Your order will be processed in 1–2 business days from the East Cost and shipped with UPS or FedEx Ground (2-5 business days). At this time, we only ship to the United States. How should I store my peptides?
In lyophilized (powder) form, store in freezer for up to 2 years. In reconstituted form, store in fridge and use in 4-8 weeks. What is your refund policy?
We are serious about customer satisfaction. If you are not happy with your order, please reach out within 30 days and we will replace or refund your order**.**
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