Growth Hormone Receptor; Somatotropin Receptor; Growth Hormone Binding Protein (GHBP)
Growth hormone (GH), also known as somatotropin, promotes body growth by binding with two GH receptors (GHRs) at the cell surface. GHRs interact with Janus kinase, signal transducers, and transcription activators to stimulate metabolic effects and insulin-like growth factor (IGF) synthesis. However, process dysfunctions in the GH–GHR–IGF-1 axis cause animal dwarfism. If, during the GH process, GHR is not successfully recognized and/or bound, or GHR fails to transmit the GH signal to IGF-1, the GH dysfunction occurs.
Cat. No. 상품명 효과 Purity Chemical Structure
HY-P0089A
Human growth hormone-releasing factor TFA Activator 99.49% Human growth hormone-releasing factor TFA (Growth Hormone Releasing Factor human TFA) is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary.
HY-P3304
MR 409 Agonist 99.98% MR 409 is a selected growth hormone-releasing hormone (GHRH) agonist. MR 409 has remarkable neuroprotective effects through enhancing endogenous neurogenesis in cerebral ischemic mice. MR 409 also inhibits the in vivo growth of lung cancer.
HY-P3397A
JV-1-36 acetate Antagonist 99.93% JV-1-36 acetate is a growth hormone-releasing hormone (GHRH) antagonist. JV-1-36 acetate inhibits the production of reactive oxygen species in A549 lung cancer cells. JV-1-36 can be used to study the effect of GHRH antagonists in vitro .
HY-164419A
Atesidorsen sodium Inhibitor 98.58% Atesidorsen sodium is a second-generation, antisense oligomer designed to inhibit translation of human growth hormone receptor (GHR) mRNA
HY-131514
L-Ornithine 2-oxoglutarate Activator L-Ornithine 2-oxoglutarate (Ornithine alpha-ketoglutarate) is a nutritional compound that is a salt of amino acids with antioxidant and anti-inflammatory effects. L-Ornithine 2-oxoglutarate stimulates the production of insulin and growth hormone, and promotes intracellular amino acid transport and protein synthesis.
HY-153485C
Cimdelirsen sodium scrambled negative control Inhibitor Cimdelirsen sodium scrambled negative control is the sequence scrambled negative control of Cimdelirsen sodium.
HY-159697B
ISIS 532401 sodium scrambled negative control ISIS 532401 sodium scrambled negative control is the sequence scrambled negative control of ISIS 532401 sodium.
HY-P0089
Human growth hormone-releasing factor Activator 98.63% Human growth hormone-releasing factor (Growth Hormone Releasing Factor human) is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary.
HY-P1460
His-[D-2-ME-Trp]-Ala 99.92% His-[D-2-ME-Trp]-Ala is a fragment of the growth hormone hexarelin.
HY-RS05413
GHRH Human Pre-designed siRNA Set A
GHRH Human Pre-designed siRNA Set A contains three designed siRNAs for GHRH gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
HY-159697A
ISIS 532401 sodium ISIS 532401 sodium is an oligonucleotide that can target GHr.
HY-159697
ISIS 532401 ISIS 532401 is an oligonucleotide that can target GHr.
HY-P3594
[His1,Nle27] GHRF (1-32), amide, human Activator [His1,Nle27] GHRF (1-32), amide, human is a Growth hormone releasing hormone (GHRH) analog. [His1,Nle27] GHRF (1-32), amide, human has great receptor affinity for GHRHR.
HY-153485
Cimdelirsen Inhibitor Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.
HY-P3595
GHRF, porcine Activator GHRF, porcine is a growth hormone releasing factor (GHRF) peptide (porcine). GHRF binds to GHSR and induces the release of growth hormone.
HY-164419
Atesidorsen Inhibitor Atesidorsen is a second-generation, antisense oligomer designed to inhibit translation of human growth hormone receptor (GHR) mRNA
HY-153485A
Cimdelirsen sodium Inhibitor Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.
HY-P3397
JV-1-36 Antagonist JV-1-36 is a growth hormone-releasing hormone (GHRH) antagonist. JV-1-36 inhibits the production of reactive oxygen species in A549 lung cancer cells. JV-1-36 can be used to study the effect of GHRH antagonists in vitro .
HY-RS05412
GHR Human Pre-designed siRNA Set A Inhibitor
GHR Human Pre-designed siRNA Set A contains three designed siRNAs for GHR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
HY-RS23191
Ghrh Rat Pre-designed siRNA Set A
Ghrh Rat Pre-designed siRNA Set A contains three designed siRNAs for Ghrh gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.