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References For Further Reading (1) S J Lee (2004) Regulation of muscle mass by myostatin – Annual Review of Cell & Developmental Biology, 2004, Volume 20, Pages 61-86. (2) Chunxia Zhao, Chunping Qiao, Ru-Hang Tang, Jiangang Jiang, et al (2015) Overcoming Insulin Insufficiency by Forced Follistatin Expression in β-cells of db/db Mice – Molecular Therapy, 2015 May, Volume 23 (Issue 5), Pages 866-874. (3) Chitra C. Iyer, Deepti Chugh, Prameela J. Bobbili, et al (2021) Follistatin-induced muscle hypertrophy in aged mice improves neuromuscular junction innervation and function – Neurobiology of Aging, Volume 104, August 2021, Pages 32-41. (4) Hélène Gilson, Olivier Schakman, Stéphanie Kalista, Pascale Lause, et al (2009) Follistatin induces muscle hypertrophy through satellite cell proliferation and inhibition of both myostatin and activin – American Journal of Physiology, Endocrinology and Metabolism, 2009 Jul, Volume 297 (Issue 1), Pages E157-64. (5) D M de Kretser, M P Hedger, K L Lovela

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Study findings do not automatically establish clinical benefit, safety, dosing, or suitability for an individual.

References For Further Reading

(1) S J Lee (2004) Regulation of muscle mass by myostatin – Annual Review of Cell & Developmental Biology, 2004, Volume 20, Pages 61-86.

(2) Chunxia Zhao, Chunping Qiao, Ru-Hang Tang, Jiangang Jiang, et al (2015) Overcoming Insulin Insufficiency by Forced Follistatin Expression in β-cells of db/db Mice – Molecular Therapy, 2015 May, Volume 23 (Issue 5), Pages 866-874.

(3) Chitra C. Iyer, Deepti Chugh, Prameela J. Bobbili, et al (2021) Follistatin-induced muscle hypertrophy in aged mice improves neuromuscular junction innervation and function – Neurobiology of Aging, Volume 104, August 2021, Pages 32-41.

(4) Hélène Gilson, Olivier Schakman, Stéphanie Kalista, Pascale Lause, et al (2009) Follistatin induces muscle hypertrophy through satellite cell proliferation and inhibition of both myostatin and activin – American Journal of Physiology, Endocrinology and Metabolism, 2009 Jul, Volume 297 (Issue 1), Pages E157-64.

(5) D M de Kretser, M P Hedger, K L Loveland, and D J Phillips (2002) Inhibins, activins and follistatin in reproduction – Human Reproduction Update, 2002 Nov-Dec, Volume 8 (Issue 6), Pages 529-41.

(6) Helge Amthor, Raymond Macharia, Roberto Navarrete, Markus Schuelke, et al (2007) Lack of myostatin results in excessive muscle growth but impaired force generation – Proceedings of the National Academy of Sciences of United States of America, 2007 Feb 6, Volume 104 (Issue 6), Pages 1835-40.

(7) Alexandra C McPherron and Se-Jin Lee (2002) Suppression of body fat accumulation in myostatin-deficient mice – Journal of Clinical Investment, 2002 Mar 1, Volume 109 (Issue 5), Pages 595–601.

(8) Max D Knickmeyer, Juan L Mateo, Priska Eckert, Eleni Roussa, et al (2018) TGFβ-facilitated optic fissure fusion and the role of bone morphogenetic protein antagonism – Open Biology, 2018 Mar, Volume 8 (Issue 3), Pages 170134.

(9) Yann S Gallot, Anne-Cécile Durieux, Josiane Castells, Marine M Desgeorges, et al (2014) Myostatin gene inactivation prevents skeletal muscle wasting in cancer – Cancer Research, 2014 Dec 15, Volume 74 (Issue 24), Pages 7344-56.

(10) Lei Shi, Jeyna Resaul, Sioned Owen, Lin Ye, and Wen G Jiang (2016) Clinical and Therapeutic Implications of Follistatin in Solid Tumours – Cancer Genomics & Proteomics, 2016, Volume 13 (Issue 6), Pages 425-435.

(11) C Zabkiewicz, J Resaul, R Hargest, W Guo Jiang, and L Ye (2017) Increased Expression of Follistatin in Breast Cancer Reduces Invasiveness and Clinically Correlates with Better Survival – Cancer Genomics Proteomics, 2017 Jul-Aug; 14 (4): Pages 241-251.

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