Growth Hormone
Name
Description
Product #
Price
Quantity
Shipping Method
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Description:
Growth Hormone Human Recombinant
GH1, GH, GHN, GH-N, hGH-N,Pituitary growth hormone, Growth hormone 1, Somatotropin.
Product # :
CYT-202
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
GH Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 191 amino acids and having a molecular mass of 22kDa. Growth Hormone is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
GH protein lyophilized from a 0.2μm filtered concentrated solution containing mannitol, and glycine.
Purity
Greater than 96.0% as determined by SDS-PAGE.
Biological Activity
The ED50 was determined by the proliferation assay of rat lymphoma NB2-11 cells and was found to be less than 0.1ng/ml.
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Introduction Synonyms Physical Appearance Stability Solubility Amino Acid Sequence
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
GH Binding Protein Rat Recombinant
GHBP, GH receptor.
Product # :
CYT-933
Price :
Quantity :
Shipping Method :
Shipped with Ice Packs
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description source formulation purity More Info
Description
GHBP produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 255 amino acids (19-265.a.) and having a molecular mass of 29.4kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).GHBP is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Source
Sf9, Baculovirus cells.
Formulation
GHBP protein solution (0.5mg/ml) contains phosphate buffered saline (pH7.4) and 10% glycerol.
Purity
Greater than 95.0% as determined by SDS-PAGE.
More Info
Introduction Synonyms Physical Appearance Stability Amino Acid Sequence
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Binding Protein Rabbit Recombinant
GHR, GHBP, GH receptor, Somatotropin receptor.
Product # :
CYT-593
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
Growth Hormone Binding Protein Rabbit Extracellular Domain Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 249 amino acids and having a molecular mass of 28 kDa. GHBP Rabbit is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
The Growth Hormone Binding Protein Rabbit was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3.
Purity
Greater than 98.0% as determined bySDS-PAGE.
Biological Activity
Evidenced by its ability of forming 2:1 complex with non-primate Growth Hormones.
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Introduction Synonyms Physical Appearance Stability Solubility Amino Acid Sequence
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Binding Protein Ovine Recombinant
GHR, GHBP, GH receptor, Somatotropin receptor.
Product # :
CYT-470
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
Growth Hormone Binding Protein Ovine Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 244 amino acids and having a molecular mass of 28 kDa. GHBP is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
GHBP was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3.
Purity
Greater than 98.0% as determined by: (a) Gel filtration analysis. (b) Analysis by SDS-PAGE.
Biological Activity
fully biologically active as evidenced by its ability of forming 2:1 complex with Human GH.
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Introduction Synonyms Physical Appearance Stability Solubility Amino Acid Sequence
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Binding Protein Mouse Recombinant
GHR, GHBP, GH receptor, Somatotropin receptor.
Product # :
CYT-1256
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
Growth Hormone Binding Protein Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 247 amino acids and having a molecular mass of 28 kDa. GHBP Mouse is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
The Growth Hormone Binding Protein Mouse was lyophilized from a concentrated (1mg/ml) solution with 0.5mg/ml NaHCO3.
Purity
Greater than 95.0% as determined by:
(a) Gel filtration analysis.
(b) Analysis by SDS-PAGE.
Biological Activity
fully biologically active as evidenced by its ability of forming 2:1 complex with human and non-primate GHs.
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Synonyms Physical Appearance Stability Solubility Amino Acid Sequence Background
GHBP is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon 3 and has been well-characterized. Mutations in GHBP have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short height.
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Binding Protein Human Recombinant, Sf9
GHR, GHBP, GHIP.
Product # :
CYT-1152
Price :
Quantity :
Shipping Method :
Shipped with Ice Packs
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description source formulation purity biological activity More Info
Description
GHBP Human produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 254 amino acids (19-264aa) and having a molecular mass of 29.4kDa.GHBP is fused to a 8 amino acid His tag at C-terminus and purified by proprietary chromatographic techniques.
Source
Sf9, Baculovirus cells.
Formulation
The GHBP solution (1mg/ml) contains 10% Glycerol and Phosphate-Buffered Saline (pH 7.4).
Purity
Greater than 95.0% as determined by SDS-PAGE.
Biological Activity
Measured by ability to inhibit GH-induced proliferation assay using Nb2-11 Rat lymphoma cells in the presence of 1.25ng/ml of human growth hormone. The ED50 for this effect is equal or less than 10ng/ml.
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Introduction Synonyms Physical Appearance Stability Amino Acid Sequence
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Binding Protein Human Recombinant, His Tag
Growth Hormone Receptor, Growth Hormone Binding Protein, Somatotropin Receptor GH Receptor, Serum Binding Protein, GHBP, GHIP.
Product # :
CYT-921
Price :
Quantity :
Shipping Method :
Shipped with Ice Packs
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description source formulation purity biological activity More Info
Description
GHBP produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 254 amino acids (19-264a.a.) and having a molecular mass of 29.4kDa.GHBP is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Source
Sf9, Insect cells.
Formulation
GHBP protein solution (1mg/ml) contains phosphate buffered saline (pH7.4) and 10% glycerol.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Biological Activity
The ED50 range ≤ 10ng/ml and is measured by ability to inhibit GH-induced proliferation assay using Nb2-11 Rat lymphoma cells in the presence of 1.25ng/ml of human growth hormone.
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Introduction Synonyms Physical Appearance Stability Amino Acid Sequence
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
GHBP Human Recombinant
Product # :
CYT-238
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
GHBP Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 248 amino acids and having a molecular mass of 28107.01 Dalton. GHR is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
GHBP was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3.
Purity
Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Biological Activity
GHBP is fully biologically active as evidenced by its ability of forming 2:1 complex with G.H.
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Introduction Physical Appearance Stability Solubility Amino Acid Sequence Protein content
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Mutant Zebrafish Recombinant
GH1, GH, GHN, GH-N, hGH-N, Pituitary growth hormone, Growth hormone 1, Somatotropin.
Product # :
CYT-709
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity More Info
Description
Somatotropin Zebrafish Mutant G113R Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 185 amino acids with an additional Ala at the N-terminus and having a molecular mass of 21.18 kDa. The Zebrafish Mutant G113R Recombinant is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
The protein was lyophilized from a concentrated (1mg/ml) solution with 0.5% NaHCO3 pH-8.
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
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Introduction Synonyms Physical Appearance Stability Solubility Amino Acid Sequence
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Zebrafish Recombinant
GH1, GH, GHN, GH-N, hGH-N, Pituitary growth hormone, Growth hormone 1, Somatotropin.
Product # :
CYT-710
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
Somatotropin Zebrafish Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 185 amino acids with an additional Ala at the N-terminus and having a molecular mass of 21.18 kDa. The Zebrafish Recombinant is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
The protein was lyophilized from a concentrated (1mg/ml) solution with 0.05% NaHCO3 pH-8.
Purity
Greater than 99.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Biological Activity
Zebrafish Growth-Hormone is biologically active in PDF-P1 3B9 cells stably transfected with rabbit GH receptors.
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Introduction Synonyms Physical Appearance Stability Solubility Amino Acid Sequence
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
GH Rat Recombinant
GH1, GH, GHN, GH-N, hGH-N,Pituitary GH, GH-1.
Product # :
CYT-296
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity More Info
Description
GH Rat Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 190 amino acids and having a molecular mass of 21810 Dalton. GH is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
The protein (1mg/ml) was lyophilized after extensive dialyses against 5mM phosphate buffer, 5mg mannitol and 1mg glycine.
Purity
Greater than 97.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
More Info
Introduction Synonyms Physical Appearance Stability Solubility
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Rainbow Trout (Oncorhynchus mykiss) Recombinant
GH1, GH, GHN, GH-N, hGH-N, Pituitary growth hormone, Growth hormone 1, Somatotropin.
Product # :
CYT-1010
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
Somatotropin Rainbow Trout (Oncorhynchus mykiss) Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 188 amino acids with an additional Ala at the N-terminus and having a molecular mass of 21, 535 Dalton. The Rainbow Trout (Oncorhynchus mykiss) Growth-Hormone Recombinant is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
The protein was lyophilized from a concentrated (1mg/ml) solution with 0.5% NaHCO3. Adjusted to pH-8.
Purity
Greater than 95.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Biological Activity
Somatotropin Rainbow Trout (Oncorhynchus mykiss) Recombinant is biologically active in PDF-P1 3B9 cells stable transfected with rabbit GH receptors, though its activity is about 10 fold lower than that of human GH.
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Introduction Synonyms Physical Appearance Stability Solubility Amino Acid Sequence
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Porcine Recombinant
GH1, GH, GHN, GH-N, hGH-N,Pituitary growth hormone, Growth hormone 1, Somatotropin, pST.
Product # :
CYT-519
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
Porcine-Somatotropin Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 190 amino acids and having a molecular mass of 21730 Dalton. Growth Hormone is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
The Growth-hormone (1 mg/ml) was lyophilized after extensive dialyses against 0.34 mg sodium phosphate buffer (0.02 mg sodium phosphate monobasic & 0.32 mg sodium phosphate dibasic).
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Biological Activity
Somatotropin contains 3 units/mg.
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Introduction Synonyms Physical Appearance Stability Solubility Amino Acid Sequence
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Ovine Recombinant
GH1, GH, GHN, GH-N, hGH-N,Pituitary growth hormone, Growth hormone 1, Somatotropin.
Product # :
CYT-237
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
Growth Hormone Ovine Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 191 amino acids and having a molecular mass of 21833 Dalton. The GH Ovine Recombinant is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
The protein was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3.
Purity
Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Biological Activity
The activity as determined by the dose-dependant stimulation of the proliferation FDCP13B9 cells.
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Introduction Synonyms Physical Appearance Stability Solubility Amino Acid Sequence Protein content
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
GH Mouse Recombinant
GH1, GH, GHN, GH-N, hGH-N, Pituitary GH, GH-1.
Product # :
CYT-540
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity More Info
Description
Growth Hormone Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 190 amino acids and having a molecular mass of 22 kDa. Mouse GH is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
Mouse Growth Hormone Recombinant Lyophilized from a 0.2 μm filtered solution of 20mM HEPES, 4% Sucrose, 4% Mannitol, 0.02% Tween 80, pH 8.0.
Purity
Greater than 95.0% as determined by SDS-PAGE.
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Introduction Synonyms Physical Appearance Stability Solubility
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Human Recombinant, Plant
GH1, GH, GHN, GH-N, hGH-N,Pituitary growth hormone, Growth hormone 1, Somatotropin.
Product # :
CYT-053
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
GH human Recombinant produced in Nicotiana benthamiana plant is a single chain containing 205 amino acids (molecular formula C1025H1570N280O306S7) and 6-His-tag at the N-terminal having the total molecular mass of 22.9kDa.
Source
Nicotiana benthamiana plant
Formulation
Lyophilized from 1mg/ml solution in PBS 0.05M buffer at pH 7.5.
Purity
Greater than 97.0% as determined by Analysis by SDS-PAGE.
Biological Activity
The biological activity of human Growth Hormone is measured by cell proliferation using Nb2-11 cells. ED50 < 0.04-0.1 ng/mL.
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Introduction Synonyms Physical Appearance Stability Solubility Amino Acid Sequence
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Human Recombinant, HEK
GH1, GH, GHN, GH-N, hGH-N,Pituitary growth hormone, Growth hormone 1, Somatotropin.
Product # :
CYT-091
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
Growth Hormone Human Recombinant produced in HEK cells is a non-glycosylated monomer, having a total molecular weight of 22kDa.The GH is purified by proprietary chromatographic techniques.
Source
HEK.
Formulation
The GH was lyophilized from 1.13mg/ml in 1xPBS.
Purity
Greater than 95% as obsereved by SDS-PAGE.
Biological Activity
The activity was determined by the dose dependent stimulation of the proliferation of rat lymphoma line Nb2-11 cells (prolactin indicator cell line), the ED50 is 0.1ng/ml.
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Introduction Synonyms Physical Appearance Stability Solubility
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Pituitary 20kDa Human Recombinant
GH1, GH, GHN, GH-N, hGH-N,Pituitary growth hormone, Growth hormone 1, Somatotropin.
Product # :
CYT-259
Price :
Quantity :
Shipping Method :
Shipped with Ice Packs
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description source formulation purity More Info
Description
Growth Hormone 20KDa Pituitary Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 177 amino acids ( 27-202 a.a. ) and having a molecular mass of 20322 Dalton. HGH-20kDa is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
HGH-20K solution contains PBS pH-7,4, and 10% glycerol.
Purity
Greater than 95% as determined by SDS-PAGE.
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Introduction Synonyms Physical Appearance Stability Amino Acid Sequence
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Gilthead Seabream Recombinant
GH1, GH, GHN, GH-N, hGH-N, Pituitary growth hormone, Growth hormone 1, Somatotropin.
Product # :
CYT-529
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
Somatotropin Gilthead Seabream Recombinant Sparus Aurata produced in E.Coli is a single, non-glycosylated polypeptide chain containing 188 amino acids with an additional Ala at the N-terminus and having a molecular mass of 21.4 kDa. The Gilthead Seabream Growth-Hormone Recombinant is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
The protein was lyophilized from a concentrated (1mg/ml) solution with 0.02% NaHCO3.
Purity
Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Biological Activity
Binding assays of the 125I-labeled gilthead seabream GH to dolphin fish liver microsomal fraction resulted in high specific binding characterized by a Ka of 1.93 nM and a Bmax of 540 fmol/mg microsomal fraction protein. Recombinant gilthead seabream Growth Hormone, like ovine placental lactogen, exhibited growth-stimulating activity when applied orally to Sparus aurata larvae or intraperitoneally to juvenile fish.
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Introduction Synonyms Physical Appearance Stability Solubility Amino Acid Sequence
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
GH Chicken Recombinant
GH1, GH, GHN, GH-N, hGH-N,Pituitary GH, GH 1,
Product # :
CYT-430
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
GH Chicken Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 191 amino acids with an additional Ala at its N-terminus and having a molecular mass of 22255 Dalton. GH Chicken recombinant is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
The protein was lyophilized from a concentrated (1mg/ml) solution with 0.3% NaHCO3 adjusted to pH 8.
Purity
Greater than 99.0% as determined by: (a) Analysis by SDS-PAGE gel. (b) Analysis by SEC-HPLC.
Biological Activity
GH Chicken Recombinantis fully biologically active in homologous assays and in PDF-P1 3B9 cells stably transfected with rabbit GH receptors.
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Introduction Synonyms Physical Appearance Stability Solubility Amino Acid Sequence Protein content
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Carp Recombinant
GH1, GH, GHN, GH-N, hGH-N,Pituitary growth hormone, Growth hormone 1, Somatotropin.
Product # :
CYT-297
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
Growth Hormone Carp Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 188 amino acids & having a molecular mass of 21,408 Dalton. Growth Hormone Carp is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
The GH Carp was lyophilized from a concentrated (1mg/ml) solution with 0.3% NaHCO3 adjusted to pH 8.
Purity
Greater than 95.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Biological Activity
Carp GH is biologically active in rat 3T3 F442A preadipocytes, though its activity is 15-fold lower compared to bovine GH, but it is equally potent in vivo in promoting carp growth (Fine et al.1993). Furthermore, carp GH forms 1:2 complex with the extra cellular domain of ovine growth hormone receptor.
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Introduction Synonyms Physical Appearance Stability Solubility Amino Acid Sequence
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Bovine Recombinant
BGH, BST, rBGH, rBST, Bovine Somatotropin, Bovine GH, Growth hormone, GH1.
Product # :
CYT-636
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
Growth Hormone Bovine Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 191 amino acids and having a molecular mass of 21.8 kDa. The GH Bovine Recombinant is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
The Bovine Growth Hormone protein was lyophilized from a concentrated (1mg/ml) solution with 4.5mM NaHCO3 adjusted to pH 8-9.
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Biological Activity
The activity as determined by the PDFP13B9 cells stably transfected with rabbit GH receptors. Bovine GH is also capable of forming a 1:2 complex with the recombinant ovine growth hormone receptor extracellular domain (ECD).
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Introduction Synonyms Physical Appearance Stability Solubility Protein content
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Anatagonist Rat Recombinant
GH1, GH, GHN, GH-N, hGH-N, Pituitary growth hormone, Growth hormone 1, Somatotropin.
Product # :
CYT-1250
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
Rat Growth Hormone Anatagonist produced in E.Coli is a single, non-glycosylated polypeptide chain containing 191 amino acids and having a molecular mass of 22 kDa. GH Antagonist Rat is purified by proprietary chromatographic techniques.
Source
Escherichia coli.
Formulation
The protein was lyophilized from a concentrated (1mg/ml) solution with 0.0045M NaHCO3.
Purity
Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC
(b) Analysis by Gel Filtration.
(c) Analysis by SDS-PAGE.
Biological Activity
Plays a role as antagonist using an in vitro bioassay in PDF-P1 3B9 cells stably transfected with rabbit GH receptors. It is capable of forming a 1:1 complex with the recombinant ovine growth hormone receptor extracellular domain and binds to this ECD with affinity similar the the wild type rGH.
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Synonyms Physical Appearance Stability Solubility Amino Acid Sequence Background
GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with 4 other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which was evolved by a series of gene duplications. The 5 genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the 5 growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other 4 genes in the growth hormone locus. Protein content
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Antagonist Ovine Recombinant
GH1, GH, GHN, GH-N, hGH-N, Pituitary growth hormone, Growth hormone 1, Somatotropin.
Product # :
CYT-215
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
Somatotropin Ovine Antagonist Recombinant G119R produced in E.Coli is a single, non-glycosylated polypeptide chain containing 191 amino acids and having a molecular mass of 22 kDa. The Somatotropin Ovine Antagonist Recombinant is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
The protein was lyophilized from a concentrated (1mg/ml) solution with 0.0045M NaHCO3, pH 9.
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC (b) Analysis by Gel Filtration. (c) Analysis by SDS-PAGE.
Biological Activity
GH G119R acts as antagonist using an in vitro bioassay in PDF-P1 3B9 cells stably transfected with rabbit GH receptors. It is capable of forming a 1:1 complex with the recombinant ovine growth hormone receptor extracellular domain (ECD) and binds to this ECD with affinity similar the the wild type oGH.
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Introduction Synonyms Physical Appearance Stability Solubility Amino Acid Sequence Protein content
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Antagonist Chicken Recombinant
GH1, GH, GHN, GH-N, hGH-N, Pituitary growth hormone, Growth hormone 1, Somatotropin.
Product # :
CYT-538
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity biological activity More Info
Description
Somatotropin Chicken Antagonist Recombinant mutein G119R produced in E.Coli is a single, non-glycosylated polypeptide chain containing 191 amino acids with an additional Ala at the N-terminus and having a molecular mass of 22.3 kDa. The Chicken Growth-Hormone Antagonist Recombinant is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
The protein was lyophilized from a concentrated (1mg/ml) solution with 0.03% NaHCO3 pH-8.
Purity
Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Biological Activity
Recombinant Chicken Growth Hormone G119R mutant did not bind to ovine GHR-ECD and was devoid of any biological activity in FDC-P1 3B9 cells. However, in binding experiments that were carried out using chicken liver membranes, both ovine GH and chicken GH showed similar IC50 values in competition with 125I-ovine GH, while the IC50 of G119R mutein was 10-fold higher. These results emphasize the importance of species specificity and indicate the possibility of antagonistic activity of chGH G119R in homologous system.
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Introduction Synonyms Physical Appearance Stability Solubility Amino Acid Sequence Protein content
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description:
Growth Hormone Placental 22kDa Human Recombinant
GHL, GHV, GH-V, hGH-V, PGH.
Product # :
CYT-235
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity More Info
Description
Placental HGH 22kDa Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 192 amino acids and having a molecular mass of 22367 Dalton. Predicted pI=7.80. Placental Growth Hormone has dimished lactogenic (prolactin receptor mediated) activity characteristic to pituitary GHs. GH Placental Human Recombinant is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
The protein was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3 previously adjusted pH 8-9.
Purity
Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
More Info
Introduction Synonyms Physical Appearance Stability Solubility Amino Acid Sequence Protein content
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
View Data Sheet
Description:
Growth Hormone Placental 20kDa Human Recombinant
GHL, GHV, GH-V, hGH-V, PGH.
Product # :
CYT-337
Price :
Quantity :
Shipping Method :
Shipped at Room temp
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description source formulation purity More Info
Description
Growth Hormone Placental 20kDa Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 177 amino acids and having a molecular mass of 20498 Dalton. Predicted pI=8.20. Growth Hormone 20K placental is devoid of lactogenic (prolactin receptor mediated) activity characteristic to pituitary GHs. GH 20K placental is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Formulation
pGH 20kDa was lyophilized from a concentrated (1mg/ml) solution with0.0045mM NaHCO3 previously adjusted pH 11.
Purity
Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
More Info
Introduction Synonyms Physical Appearance Stability Solubility Amino Acid Sequence
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
About Growth Hormone:
Growth hormone (GH) is sometimes called somatotropin, or simply human growth hormone (HGH). It is known to help stimulate cell growth and reproduction, which leads to increased cell regeneration in human bodies. Therefore, it is argued that GH is essential in regular human development. As a peptide hormone, it is a type of mitogen that is specifically present in certain types of cells. There are many forms of human growth hormone found in the medicinal and pharmaceutical worlds. The most common of which is a recombinant form that’s given as a prescription drug to children with growth problems and deficiency. HGH has also been banned by many major sports and athletics committees due to the role it plays in the human body. It can be used as an anabolic steroid to elicit performance advantages in athletes.
Function Growth hormone mainly has anabolic effects on tissues in the human body. This means it tends to help build them up. The most common example of its function is the increased height of children as they grow up. Children that are small and don’t experience growth spurts are known to have a deficiency in human growth hormone. But, the function of HGH doesn’t end here. It is also known to help improve calcium retention in cells, which leads to an increase in bone strength. Furthermore, it can help improve and increase muscle mass through a process known as hypertrophy.In conjunction with this. HGH also boosts protein synthesis in the body. Human growth hormone also acts to grow all the organs in the body, with the exception of the brain. It also reduces the way the liver takes in glucose, and can play a key role in homeostasis. Another well-known function of this growth hormone is the way it acts to stimulate the immune system.
Mechanism/Interactions HGH stimulates height in children by at least two different mechanisms. The first is that GH uses some of its effects to connect with receptors on target cells, activating something known as the MAPK/ERK pathway. By doing this, growth hormone can help divide and multiple chondrocytes of cartilage. This is important because most polypeptide hormones can’t penetrate cell membranes due to them not being fat-soluble. Secondly, growth hormone helps to induce the production of IGF-1 (insulin-like growth factor 1). It does this through the JAK-STAT signaling pathway. It interacts with the liver, which is the main place where IGF-1 is produced. IGF-1 is known to help stimulate growth in many different tissues.
Structure Human growth hormone is primarily comprised of a protein weighing 22, 124 daltons. It contains 191 amino acids, and the structure can be described as having four helices. These helices are essential for interacting with the GH receptor, which helps elicit its various functions. A closer look at the structure of GH reveals that it is homologous to prolactin and chorionic somatomammotropin. There are many growth hormones present in different species, but only human growth hormone and old world monkey growth hormone will have any effect on the HGH receptor.