Boosted IGF-1 Levels: This peptide has been shown to reliably increase IGF-1 levels by stimulating sustained GH release. In one human trial, a single injection elevated IGF-1 levels for 9–11 days above baseline. Multiple doses maintained raised IGF-1 for up to 28 days. Higher IGF-1 supports tissue repair, muscle hypertrophy, and metabolic regulation, including enhanced fat metabolism (1).
Enhanced Fat Loss: Research suggests it has been shown to increase growth hormone (GH) levels 2 to 10-fold for six days after a single dose, and IGF-1 levels 1.5 to 3-fold for up to 9-11 days. Since GH promotes lipolysis (the breakdown of fat) and IGF-1 supports improved metabolism and lean tissue, these elevated hormone levels have the potential to enhance fat loss and improve body composition in humans (1).
Muscle Growth & Recovery: Scientific studies & lab-report data suggest this peptide increases growth hormone (GH) and insulin-like growth factor-1 (IGF-1), which drive protein synthesis and cell regeneration, key for muscle growth and recovery. Animal models show increases in lean body mass, improved nitrogen retention, and faster healing of soft-tissue injury. In humans, single doses elevate growth hormone and IGF-1 levels, aiding anabolic and repair processes (1).
Improved Sleep & Recovery: Research suggests it may enhance sleep and recovery by promoting growth hormone (GH) secretion, which is closely tied to deep sleep cycles. Research shows that growth hormone (GH) levels are highest during slow-wave sleep (SWS), the deepest phase of sleep (2). Deep sleep is vital for your body’s rest, recovery, and brain function. Research shows that a lack of sleep can decrease important growth factors like IGF-1, but getting enough sleep can restore them. This proves how crucial sleep is for balancing the body’s growth hormone and IGF-1 levels (3).
Skin, Hair & Anti-Aging Effects: Research shows this peptide boosts GH and IGF-1, which supports anti-aging effects and improves skin, hair, and nails. Studies suggest growth hormone (GH) and insulin-like growth factor 1 (IGF-1) stimulate collagen synthesis within skin fibroblasts and the connective tissues of tendons and muscles, helping to improve their elasticity and strength (4). IGF-1 also promotes hair follicle anagen-phase duration, upregulates anti-apoptotic proteins, and supports hair shaft growth (5).
Increased GH Secretion: The peptide stimulates the pituitary to secrete significantly more growth hormone (GH), raising both basal (trough) and mean GH levels by sustained stimulation. With the DAC moiety, the peptide’s half-life is extended to ~5.8–8 days, allowing less frequent dosing compared to native GHRH (≈30 minutes) (6).
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