Description
IGF-1 LR3 is a research peptide based on human insulin-like growth factor-1 that laboratories use to study growth-factor signalling, protein synthesis, and metabolic pathways in controlled in-vitro systems.
IGF-1 LR3 (Long R3 Insulin-Like Growth Factor-1)
This Long R3 variant includes a 13-amino-acid extension and an arginine substitution at position 3. These sequence changes reduce binding to IGF-binding proteins (IGFBPs) and support sustained availability in experimental models. For laboratory research only. Not for human use.
IGF-1 Key features
Engineered to minimise IGFBP binding and support consistent readouts in vitro. Supplied as a lyophilised solid for stability and straightforward storage. Unit size: 1 mg per vial. Each batch released only after stringent quality checks
Specifications
Product name: IGF-1 LR3 Synonyms: Long R3 IGF-1; Long Arg3 IGF-1 Molecular formula: C400H625N111O115S9 Molecular weight: 9,117.6 g/mol CAS: 946870-92-4 Form: Lyophilised powder Appearance: White to off-white solid
Handling & storage
Storage (dry): Keep vials protected from light and moisture. Reconstitution: Bring vial and diluent to room temperature. Reconstitute with Bacteriostatic Water 10 ml. Swirl gently — do not vortex. After reconstitution: Store at 2–8 °C, protect from light, use aliquots to reduce handling, and avoid repeated temperature cycling. Compatibility: Use only within research protocols that follow your lab’s SOPs and local regulations.
Looking for complementary materials? See Bacteriostatic Water 10 ml and GH-axis companions such as CJC-1295 (No DAC) 5 mg and Ipamorelin 5 mg.
About IGF-1 LR3 in research
IGF-1 LR3 retains receptor-binding characteristics of native IGF-1 while its sequence modifications help sustain activity in vitro by limiting IGFBP interactions. Consequently, researchers use it to probe cell growth and differentiation, protein synthesis, and glucose-metabolism pathways in non-clinical models.
Synthesis & quality
Manufactured via controlled, validated peptide-synthesis processes to deliver high purity and lot-to-lot consistency. Each batch undergoes identity, purity, and appearance checks before release.
Legal & safety
XL Peptides supplies materials strictly for laboratory research. Products are not medications, foods, supplements, or cosmetics; not for human or veterinary use. By purchasing, you confirm you are a qualified researcher and will handle the material in line with your institution’s policies and applicable laws.
FAQs
What is IGF-1 LR3? A modified IGF-1 peptide with a 13-residue extension and an Arg substitution at position 3, used to study growth-factor signalling in vitro.
How should I store the peptide? Keep lyophilised vials away from light and moisture. After reconstitution, store at 2–8 °C, protect from light, and avoid repeated temperature cycling.
What diluent should I use? Many labs use Bacteriostatic Water 10 ml. Always follow your lab’s SOPs.
Do you provide documentation? Yes. Batch documentation (e.g., Test Results) is available on request; if it’s not attached below, contact support and we’ll add it to your order.
Is this product for human use? No. This material is for research only and is not intended for human consumption or clinical applications.
External resources for researchers
UniProt — IGF-1 (human) overview NCBI Gene — IGF1 PubChem — CAS 946870-92-4 (search)
Related research peptides
CJC-1295 (No DAC) 5 mg Ipamorelin 5 mg Bacteriostatic Water 10 ml
Disclaimer
Used solely for in vitro experiments and cannot be:
– Used in clinical trials involving humans – Administered to humans as part of an experiment or investigation – Supplied to another party for human investigational use
XL Peptides works with various third-party laboratories to provide testing reports for all its manufactured products.
Date
Batch No
Issuing Lab
Lab Report
View QR
21-Jan-25
007001
View Report
To find out more about our testing policy, please visit our Testing page.