TB-500 (TB4, 10mg vials)
In stock
Peptide Partners
TB-500 (TB4) Kit
Your only source for Certified Endotoxin-safe TB-500
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Product Format
10mg vials
Vial Size
10mg
Vial Capacity
3 mL
Box Combinations
20mg, 50mg, 100mg
Cost per milligram
$4.90 – $6.50
Multi-vial Purity
99.76%
Endotoxin Screening
PASSED
Heavy Metals Screening
Purity Screening
Independently Tested
YES
Peptide Partners Manufacturer Id: WF03
Batch Id: TB202605
Research Studies
Study 1: Simultaneous quantification of TB-500 and its metabolites in in-vitro experiments and rats by UHPLC-Q-Exactive orbitrap MS/MS and their screening by wound healing activities in-vitro
Authors: Khandoker Asiqur Rahaman, Anca Raluca Muresan, Hophil Min, Junghyun Son, Hyung-Seop Han, Min-Jung Kang, Oh-Seung Kwon
Source: https://www.sciencedirect.com/science/article/pii/S1570023224000412
This study developed and validated a simultaneous analytical method for TB-500 and its metabolites using UHPLC-Q-Exactive orbitrap MS. The metabolism of TB-500 was investigated in human serum, various in-vitro enzyme systems, and in urine from rats. The biological activities of the parent compound and its metabolites were assessed via cytotoxicity and wound healing experiments in fibroblasts. The results indicated that Ac-LK was the primary metabolite in rats, while Ac-LKK was a long-term metabolite. No cytotoxicity was observed for the parent compound or its metabolites. Notably, only the metabolite Ac-LKKTE demonstrated significant wound healing activity compared to the control, suggesting that the reported therapeutic effects of TB-500 may be attributable to this metabolite rather than the parent form.
Scientists have developed a new method to measure TB-500 and its breakdown products in the body. TB-500 is a substance that is thought to help with healing. In this study, they looked at how TB-500 is broken down in human blood and in rats. They found that one of the breakdown products, called Ac-LKKTE, is actually what helps wounds to heal, not TB-500 itself. This is an important discovery because it could lead to new and better treatments for wounds in the future.
Study 2: Investigation of in vitro/ex vivo TB-500 metabolism, synthesis of relevant metabolites and detection limits in urine and plasma
Authors: P. Van Eenoo
Source: https://www.wada-ama.org/en/resources/scientific-research/investigation-vitroex-vivo-tb-500-metabolism-synthesis-relevant
This project aimed to characterize the human metabolism of TB-500 using in vitro (human liver microsomes and S9 fraction) and ex vivo (human plasma/serum) models. The study found that TB-500 undergoes serial cleavage at the C-terminus, while the N-terminal acetylation provides protection. The researchers synthesized three metabolites, TB-500 M(1-2), TB-500 M(1-3), and TB-500 M(1-5), and a deuterated internal standard (TB-500-d3). The limits of detection (LODs) for the synthesized metabolites were determined and implemented into a screening method for detecting peptides in urine, with LODs of 500 pg/mL for TB-500 M(1-2), 100 pg/mL for TB-500 M(1-3), and 50 pg/mL for TB-500 M(1-5).
Researchers studied how the human body breaks down TB-500, a substance sometimes used to enhance athletic performance. They used laboratory models of the human liver and blood to see what happens to TB-500. They found that the substance is broken down in a specific way, and they were able to create some of these breakdown products in the lab. This information was then used to develop a more sensitive test to detect TB-500 in urine, which is important for anti-doping efforts in sports.
Study 3: Utilizing Developmentally Essential Secreted Peptides Such as Thymosin Beta-4 to Remind the Adult Organs of Their Embryonic State—New Directions in Anti-Aging Regenerative Therapies
Authors: Klaudia Maar, Roland Hetenyi, Szabolcs Maar, Gabor Faskerti, Daniel Hanna, Balint Lippai, Aniko Takatsy, Ildiko Bock-Marquette
Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC8228050/
This review discusses the role of Thymosin Beta-4 (TB4) in regenerative processes, particularly in the context of cardiac repair. The authors highlight their findings that external administration of TB4 promotes myocardial cell migration and survival in embryonic tissue in vitro. This effect is retained post-natally and is attributed to a direct effect on cardiac cells. The mechanism of action is partly explained by the activation of Integrin-Linked Kinase (ILK) and subsequent stimulation of Akt, which inhibits myocardial cell death. The review summarizes the growing body of evidence supporting the therapeutic potential of TB4 in cardiac regeneration and its potential to influence age-related changes in the heart and blood vessels.
This paper reviews the exciting potential of a naturally occurring molecule called Thymosin Beta-4 (TB4) to help our bodies heal and even reverse some of the effects of aging. The authors’ research has shown that TB4 can encourage heart cells to move and survive, which is crucial for repairing damage after a heart attack. They found that this happens because TB4 activates a specific chain of events inside the cells that prevents them from dying. This research suggests that TB4 could be a promising new treatment for heart disease and other age-related conditions, essentially ‘reminding’ our adult organs how to heal themselves like they did when we were embryos
Storage:
All of our manufacturing partners produce peptides using the Lyophilization (Freeze Drying) process, ensuring products maintain stability for shipping and storage for 12+ months.
In lyophilized form, they are shelf-stable for many weeks. However, for long-term storage, it is recommended to store them in the freezer.
We often hear concerns about the standard “discard after 28 days of first use” disclaimer. Don’t worry, this has nothing to do with studies regarding the efficacy of specific peptides. 28 days is the FDA requirement for producers of multi-use vials to prove their bacteriostatic maintains efficacy. This minimum requirement becomes the de facto standard.
In our experience, if you use proper sterile procedures and refrigerated storage, you can continue sampling from the same reconstituted vial for 3+ months.
Third-party testing
Peptide Partners is committed to providing high-purity peptides at wholesale prices by frequently auditing its manufacturing partners using third-party laboratories. Independent analysis is vital to ensuring the quality and authenticity of your research peptides. Never trust a supplier that doesn’t submit to third-party testing. Never trust a certification that cannot be independently verified. All of the certificates that we provide can be validated on the third-party laboratory’s website.
Each product description contains a Manufacturer ID corresponding to the producer of that product. The table below contains the most recent third-party analyses for all manufacturers and peptides listed on Peptide Partners.
Current Purity certifications
Kisspeptin-10
KSS2607
VI32
2026-07-02
99.71%
Kovera
View File
Reconstitution Solution
BAC202603
WF03
2026-07-13
99.9%
Retatrutide
RTT2613
99.77%
PT-141
PT202605
2026-06-25
99.74%
Tesamorelin
TES202607
2026-06-19
99.80%
TrustPointe
KPV
KV202606
2026-06-12
99.36%
Yes
BPC-157
BC202607
99.82%
Ipamorelin
IP202606
99.98%
Semaglutide
SM202607
99.96%
RTT202606
CJC-1295 ND
CJ202606
2026-06-10
99.88%
RT202607
2026-06-09
Tirzepatide
TZ202605
99.55%
99.68%
99.70%
99.34%
99.65%
99.90%
NAD+
NDB202606
2026-05-28
GHK-Cu
CU202605
2026-05-13
99.67%
Epithalon
ET202604
99.86%
5-Amino-1MQ
AM202604
99.78%
2026-05-29
99.53%
Chromate
2026-06-11
99.22%
MOTS-c
MC202605
2026-06-08
99.94%
TB-500 (TB4)
TB202605
TES202605
99.81%
RT202605
2026-05-27
99.75%
BAC202602
2026-05-14
CJC-1295 ND / Ipamorelin
CJIP202605
99.93%
Cagrilintide
CG202607
BPC-157/TB-500
BB202605
99.73%
CU202604
BC202604
99.72%
CIT: CJC-1295 ND / Ipamorelin / Tesamorelin
CIT202604
2026-05-07
TES202604
2026-04-21
99.85%
DSIP
DS202605
KLOW Blend
KW202604
AOD-9604
AO202605
2026-04-20
CG202603
2026-04-14
MC202603
2026-04-04
RT202604
2026-04-16
99.54%
Sermorelin
SER202601
2026-04-01
Pinealon
PN202603
2026-04-03
SS-31
SS202601
Semax
SX202603
2026-03-31
99.91%
RT202603
2026-03-30
99.40%
GLOW Blend
GW202603
2026-03-25
TZ202603
2026-03-27
99.89%
BB202604
99.63%
TES202603
99.52%
2026-03-18
99.60%
Ipamorelin/CJC-1295 (No DAC)
CJIP202602
2026-02-27
99.92%
Thymosin Alpha-1
TA202602
2026-02-25
99.95%
KLOW
KW202602
2026-03-01
NDB202601
2026-02-07
SS202602
2026-02-08
MC202602
2026-02-09
99.41%
Selank
SEK202601
2026-01-29
Unbuffered NAD+
NDU202601
MZ21
2026-01-20
KV202601
IP202601
2026-01-14
TB500 (TB4)
TB202601
RT202602
2026-01-13
PT202512
2026-01-12
BioRegen
SM202601
2026-01-10
CAG202601
99.33%
TES202601
2025-12-29
BP202512
99.46%
BB202512
99.64%
GK202512
SH07
2025-12-19
99.79%
MC202512
2025-12-22
RP260130
SS202512
RP202601
DF05
CJIP202512
2025-12-09
RP202511
RP20251020
2025-11-10
RP20251001
2025-10-13
TZ20250915
2025-10-03
RP20250929
99.47%
Humanin
HP20250805
2025-09-19
YC20250807
99.87%
DS20250820
SY20250806
CJC/Ipamorelin
CI20250805
2025-09-11
99.84%
BP20250808
2025-09-05
99.99%
SM20250723
2025-08-27
TS20250722
2025-08-22
99.10%
CJ20250724
2025-08-20
99.43%
SM20250801
EJ12
IP20250721
2025-08-15
CU20250717
2025-08-09
TZ20250730
2025-08-08
ND20250503
2025-07-31
VIP
VP20250511
99.42%
CD20250708
2025-07-25
BPC/TB500
BB20250630
2025-07-17
TB20250614
Current Endotoxin Certifications
2026-06-30
Conforms
2026-06-22
2026-06-15
2026-05-18
2026-03-26
CJC-1295 ND/Ipamorelin
2026-03-17
TA202601
2026-01-28
TB500
2026-01-07
2026-01-06
2025-12-30
2025-12-08
2025-09-03
Bacteriostatic Water
BAC20250807
2025-08-11
2025-08-04
2025-07-29
2025-07-24
Current Heavy Metal Certifications
2026-07-01
2026-06-26
2026-06-13
2026-06-05
TB-500
2026-05-26
2026-05-24
2026-05-16
2026-04-26
2026-04-22
2026-05-05
2026-04-24
2026-04-02
2026-03-29
2026-01-26
2026-01-19
2026-01-08
2025-12-03
2025-11-24
2025-11-12
Current Sterility Certifications
Pass
2026-06-23
-
2026-04-12
BAC202601
2025-09-09
Meta-Z
MZR20250713
2025-08-26
Verifiable certificates
When obtaining research peptides, it is essential to validate the authenticity of the Certificate of Analysis (COA). Certificate fraud runs rampant throughout the research peptide supply community. The two most common forms are doctored images and stolen certificates. You can check for these two by making sure the third-party laboratory’s website shows that the certificate belongs to the supplier and the values haven’t been doctored. TrustPointe Analytics provides a few simple rules for verification:
Beware of fraudulent laboratories
Not only must one remain vigilant about potentially fraudulent certificates, one must also be aware that there are third-party laboratories whose results cannot be considered reliable or scientifically valid. Unfortunately, there is significant evidence to suggest that one of the most popular third-party testing labs does not use scientifically sound methodologies and, in some cases, has fabricated results. There isn’t an easy remedy for this problem, but when labs are particularly bad, there tend to be a lot of discussion threads on various social platforms.
Interpreting Endotoxin Results (via TrustPointe)
Our friends at TrustPointe have provided the following detailed explanation to help interpret the results of the endotoxin testing.
We use the Charles River Endosafe PTS system to test for bacterial endotoxins following USP <85> guidelines:
USP <85> Bacterial Endotoxin Result: <x.xx EU/mLBecause it’s reported as “<x.xx” this indicates the test did not detect endotoxin above the detection limit of the cartridge.
If a result is above the limit of detection of the cartridge, it will be reported as a number (without the “<“).
The following are suitability parameters that verify the system was working properly and the sample prep dilution is appropriate for accurate results. Peptides often interfere with endotoxin detection due to their tendency to bind or mask endotoxins, which can lead to inaccurate low results. To overcome this, samples are typically tested at a large dilution to reduce matrix interference and ensure reliable recovery and detection in compliance with USP <85>. If the dilution is not correct, the run will fail suitability and we’ll need to adjust the dilution to ensure accurate results. We provide the suitability data to customers for transparency and so they can be confident in the results.
USP <85> Sample CV %:
CV stands for coefficient of variation, a measure of repeatability.
For our lab, CV has to be <25% or the result to be considered valid
USP <85> Spike CV %:
This refers to the precision of the positive control (spiked sample).
Again, for our lab CV has to be <25% or the result to be considered valid
USP <85> Spike Recovery
This tells us how much of the known endotoxin spike was recovered from your sample.
The acceptable range is 50–200% per USP <85>
Thank you for choosing Peptide Partners.
NOTICE: All information provided above is strictly intended for educational and informational purposes. Our products are designed for research use solely and are not approved for human consumption. Please refrain from any form of ingestion.
By making a purchase from Peptide Partners, you acknowledge that you are acquiring Research Chemicals. Our products are exclusively intended for laboratory research purposes.
It is imperative that only qualified and licensed professionals handle this product. Under no circumstances should it be utilized as a drug, agricultural or pesticide product, food additive, or household chemical. Misrepresentation of this product for such purposes is strictly prohibited by law. All content on our website is provided for educational use exclusively. Any form of introduction into the human or animal body is illegal.