Recovery research fieldbook Evidence, not treatment advice
Recovery archive

Published recovery field note

MK-677 (Ibutamoren) Capsules

Oral Capsules MK-677 (Ibutamoren) capsules — a non-peptide growth hormone secretagogue for GH and IGF-1 research. Highly stable and bioavailable. $60.99 In stock Research-Grade CompoundsManufactured to research-grade standards for laboratory research use only. Discreet ShippingEvery order ships in plain, protective packaging. In-House FulfillmentOrders are inspected, packed, and shipped directly by the Heritage Labs team. Same-day dispatch on orders before 12:00 PM ET, Mon–Fri. Discreet, plain packaging. In-House Fulfillment Orders are inspected, packed, and shipped directly by the Heritage Labs team. View Certificates of Analysis → SSL 256-bit Secure Checkout For laboratory research use only. Not for human or veterinary consumption. SKU MK10C. Overview Product details. MK-677 (Ibutamoren) Capsules — Oral Growth Hormone Secretagogue MK-677, also known as ibutamoren, is a non-peptide, orally active growth-hormone secretagogue that mimics the action of ghrelin at the GHS-R1a receptor. Un

Context first

Study findings do not automatically establish clinical benefit, safety, dosing, or suitability for an individual.

Oral Capsules

MK-677 (Ibutamoren) capsules — a non-peptide growth hormone secretagogue for GH and IGF-1 research. Highly stable and bioavailable.

$60.99 In stock

Research-Grade CompoundsManufactured to research-grade standards for laboratory research use only.

Discreet ShippingEvery order ships in plain, protective packaging.

In-House FulfillmentOrders are inspected, packed, and shipped directly by the Heritage Labs team.

Same-day dispatch on orders before 12:00 PM ET, Mon–Fri. Discreet, plain packaging.

In-House Fulfillment Orders are inspected, packed, and shipped directly by the Heritage Labs team. View Certificates of Analysis →

SSL 256-bit Secure Checkout

For laboratory research use only. Not for human or veterinary consumption. SKU MK10C.

Overview

Product details.

MK-677 (Ibutamoren) Capsules — Oral Growth Hormone Secretagogue

MK-677, also known as ibutamoren, is a non-peptide, orally active growth-hormone secretagogue that mimics the action of ghrelin at the GHS-R1a receptor. Unlike the injectable peptides in this category, ibutamoren is a small molecule stable enough for oral delivery, which — together with a research half-life of roughly 24 hours — has made it one of the most studied compounds for investigating sustained activation of the GH/IGF-1 axis.

Research-Grade Compounds

Manufactured to research-grade standards for laboratory research use only.

Discreet Shipping

Every order ships in plain, protective packaging.

In-House Fulfillment

Orders are inspected, packed, and shipped directly by the Heritage Labs team.

A non-peptide ghrelin-receptor agonist

Most growth-hormone secretagogues studied in research are peptides that require reconstitution and injection. Ibutamoren is different: it is a spiropiperidine small molecule that binds the ghrelin receptor (GHS-R1a) and, in the models studied, stimulates pulsatile growth-hormone release without suppressing endogenous production. Its oral bioavailability and long duration of action make it a common tool for studying once-daily stimulation of the GH axis.

Specifications

Compound Ibutamoren (MK-677) Molecular Formula C27H36N4O5S (free base) Molecular Weight 528.66 g/mol (free base) CAS Number 159752-10-0 (free base) · 159634-47-6 (mesylate) Class Non-peptide GHS-R1a (ghrelin receptor) agonist Format 30 capsules per bottle Strength 10 mg per capsule

Research areas

GH / IGF-1 axis

Studied for its ability to elevate growth-hormone and IGF-1 levels through ghrelin-receptor activation in research models.

Ghrelin signaling

Investigated as a GHS-R1a agonist for probing the ghrelin pathway’s role in appetite, energy balance, and growth-hormone release.

Body-composition research

Examined in metabolic models for effects on lean-mass and adipose-tissue signaling associated with sustained GH/IGF-1 elevation.

Sleep-architecture and bone research

Studied for reported interactions with slow-wave sleep patterns and bone-turnover markers in preclinical models.

Research applications

Studied for GH and IGF-1 elevation via ghrelin-receptor activation Used as an oral, non-peptide alternative to injectable secretagogues in research Relevant to appetite, energy-balance, and metabolic signaling models Investigated in body-composition and lean-mass research Examined in sleep-architecture and bone-turnover research models

For research use only. Not for human consumption.

For laboratory research use only. Not for human or veterinary use. This product is not a drug or supplement and is not intended to diagnose, treat, cure, or prevent any disease.

Connected topics

Follow this recovery question