Compound: Insulin-Like Growth Factor-1 Long Arginine 3 (IGF-1 LR3)
Concentration: 100mcg per vial
Format: Lyophilized Powder (Strictly for In-Vitro Laboratory Use)
Chemical Classification: Recombinant Growth Factor Analog
Chemical Profile: IGF-1 LR3 is a synthetic, modified version of the naturally occurring Insulin-Like Growth Factor-1. Structurally, it differs from native IGF-1 in two key ways: the addition of 13 amino acids to the N-terminal end and the substitution of Glutamic Acid with Arginine at position 3. These modifications drastically alter its pharmacokinetics. Unlike native IGF-1, the LR3 variant does not bind strongly to IGF Binding Proteins (IGFBPs). In biological systems, this lack of binding affinity prevents rapid clearance, resulting in a half-life approximately 120 times longer than endogenous IGF-1. This stability makes it a highly potent reagent for sustaining cellular signaling in culture media and animal models.
Sequence: MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA Molecular Formula: C400H625N111O115S9 Molecular Weight: 9,117.5 g/mol CAS Number: 946870-92-4
Monthly subscription ten vials of 100 mcg for a total of 1000 mcg was $450 now $275